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Unlocking Structure-Property Relationships in Composite Semiconducting Nanopa...
Colloidal dispersions of organic semiconducting nanoparticles (NPs) have shown promise for the generation of active layers in organic solar cells.Composite NPs containing a... -
On the structure and composition of non-lamellar lipid-based liquid crystalli...
Liquid crystalline particles consisting of glycerol dioleate (GDO) / soy phosphatidylcholine (SPC) mixture and stabilised by polysorbate 80 (P80) have proven to be suitable as... -
SANS studies of mixed phsopholipid:sterol vesicles and their interaction with...
The increasing incidence of pathogenic fungi resistant to treatment with amphotericin B (AmB) has created a demand for novel anti-fungal agents that can circumvent the... -
Effect of shear and charged polymers on cellulose microfibrils
Cellulose is an important natural material used in many industrial applications, such as food and medicine. Cellulose micro-fibrils (CMF) are produced from wood, plants, and... -
Peptide resistance in asymmetric MRSA-mimetic vesicles
We have been investigating the influcence of the cationic staphylococcal lipid lysyl-phosphatidylglycerol (L-PG) on bacterial resistance to antimicrobial peptides (AMPs). Using... -
A new approach to viscosity enhancement of oils and CO2
Due to the naturally low viscosity of liquid CO2 (0.1-1.0 cP pressure/temperature dependent) the CO2 is prone to ¿fingering¿, limiting the efficiency of CO2-EOR [1]. In order to... -
The effect of particles on the structure of mucin ¿understanding the challeng...
Progress in the development of nano-sized hybrid therapeutics and nano-sized drug delivery systems - "nanomedicines" - over the last decade has been remarkable. One key... -
SANS evaluation of novel nanocolloidal drug carriers
With the beamtime requested we plan to employ small-angle neutron scattering (SANS) to study novel nanocolloidal drug carriers prepared using lipids, surfactants and... -
Micellization in mixtures of surfactants used in fire-fighting foams
The aim is to probe the mixed micellar compositions of three common industrial fluorotelomer surfactants used in fire-fighting foam formulations (Figure 1) using contrast... -
Mixed micelles of nonionic and metallosurfactants (P123/CTAF) as porogens of ...
Non-ionic/metallosurfactant (P123/CTAF) mixed micelles are used as templates for the hydrothermal synthesis of mesoporous ferrisilicate materials. It was hypothesized that... -
SANS contrast measurements on important protein/DNA interactions from RCaH
This proposal is to perform SANS contrast measurements on three protein/DNA interactions currently worked on at the Research Complex at Harwell. This is part of an ongoing... -
Interaction of a pH-sensitive Polymer with a Model Lipid Membrane in the Form...
This SANS experiment was proposed by 4 PhD students from 3 different institutions in a Marie-Curie Training Network. They are all in the second year of their PhD and their... -
Polymer layer structure in stabilised metal nanoparticles for heterogenous ca...
The controlled synthesis of precious metal nanoparticles of the appriopriate chemical composition, optimised size and morphology for use in catalysis is an ongoing experimental... -
W/CO2 nanodispersions as an energy-saving nanoreactor separable by pressure a...
Recent studies implied an unusual headgroup (HG)-free, fluorocarbon (FC) surfactant Nohead FC6-HC4 to form stable, W/CO2 nanodispersions (W/C NDs). With the unusual surfactant... -
Understanding the interfacial behaviour of bile salts to better engineer lipi...
The current project aims to 1) elucidate how bile salts (BS) structure influences their interfacial behaviour and role during lipolysis; 2) to study the potential ability of... -
Mechanism of charging metal oxide colloids in non-polar solvents
Contrast-variation SANS (CV SANS) will be used to determine how surfactant inverse micelles interact with model metal oxide colloids. By using deuterated surfactant (D-AOT) with... -
Mechanism of fibrous aggregate formation of caseinates as a function of proce...
This dataset has no description
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Contrast variation SANS to understand drug directed assembly of multi lamella...
Recurring infection following dental interventions such as fillings is the most common reason for failure, leading to further treatments including root canal therapy, where the... -
Investigating the internal structure of two-component polymer nanoparticles f...
The elucidation of the compositional profile inside the polymer nanoparticles is of critical importance for applications such as water processable organic solar cells. In order... -
Conformational Evaluation of Biodegradable Model Polymer-Drug Conjugates
Previous SANS studies of anti-cancer polymer-drug conjugates (PDCs) (HPMA-Doxorubicin) identified a correlation between conjugate solution conformation and clinical results. The...