-
Contrast Variation Experiments for Probing the Structure of Pickering Nanoemu...
Polymerisation-induced self-assembly is an efficient and versatile method of producing functional block copolymer spheres, worms and vesicles in a range of media (e.g. water,... -
Protein-decorated superparamagnetic iron oxide nanoparticles
The aim of this research is to understand the structural confirmation of dextran coated iron oxide (Fe3O4) nanoparticles in the presence of Bovine serum albumin (BSA) in aqueous... -
Solution aggregation of short peptide amphiphiles
Short peptide sequences consisting of hydrophobic and hydrophilic amino acid units are capable of self-assembly to lead to interfacial adsorption and solution nano-aggregation.... -
AOT stabilized aqueous ferrofluids
The aim of the experiment is to employ SANS to study the physical properties of a novel and very stable aqueous Fe3O4 ferrofluid system stabilized by the commercially available... -
Structure of Cellulose Nanofibril Gels with Alcohols
Our group has been working partially oxidized cellulose nanofibrils which form gels in aqueous formulations. Recently we have observed that these fibrils also gel when dialysed... -
Investigation of cement pore structure evolution in underground repository co...
It is proposed that radioactive waste generated in the Netherlands be buried underground in Boom clay formations. As this will need to be stored for hundreds of thousands of... -
Impact of particle properties on the structure of supramolecular hydrogels
For biomaterial applications, it is important that the properties of self-assembled hydrogels are well controlled and match the requirements of the application. The influence of... -
Investigating liposome sensitivity towards phospholipases for applications in...
Liposomes are lipid-based, water-filled vesicles with wide-ranging applications in diagnostics and drug delivery. Phospholipases (PLs) are enzymes that cleave specific bonds in... -
Pickering emulsions stabilized with oxidised cellulose nanofibrils and starch
Our group has been working functionalised cellulose nanofibrils which form gels in aqueous formulations. Previously we have used these fibrils to stabilise oil-in-water... -
Structural development of magnetite chains
One dimensional (1D) magnetic nanostructures exhibit anisotropic magnetic properties and thereby differ from unstructured materials. However, magnetic chains are energetically... -
Cationic & Nonionic Micelles in Deep Eutectic Solvents
Deep Eutectic Solvents (DES) are molecular mixtures similar to ionic liquids, having melting points below room temperature. DES share many of the features of ionic liquids (low... -
Mixed micelles with "green" surfactants
This proposal aims to explore aqueous phase structures and compositions of a series of mixed surfactants. Although standard surfactant mixtures have been extensively studied... -
Effect of drug on the micelles formed by ionic surfactants
The aim of the study is to use SANS in combination with contrast variation to determine the effect of solubilising the lipophilic drug, testosterone propionate, in micelles... -
Self-assembly of GFP-HMPA protein polymer conjugates: Effect of polymer hydro...
Conjugation of therapeutic proteins to polymers is well established but most methods result in multi-site and multiple conjugation, crosslinking resulting in lack of orientation... -
Molecular Collapse and Conformation of Low Molecular Mass Polyacrylic Acid an...
There is conflicting information about properties of polycrylic acid and its behaviour in aqueous solution. This proposal for an investigation by SANS that is directed at... -
How do polymeric de-emulsifiers work? Contrast variation studies with model w...
The project is to understand fundamental structure-performance relationships of chemical demulsifiers in water-in-crude oil (w/o) systems. In particular, to understand how... -
Small Angle Neutron Scattering Study of the Adsorption of Amine ¿functionalis...
Amine-functionalised poly(alkylene oxides) are used extensively as swelling inhibitors in water-based drilling fluids. This study will broaden our understanding of the mechanism... -
Characterisation of novel, sequence specific protein/protein and protein/DNA ...
Gene (nucleic acid) delivery to the cytosol or nucleus of a cell is, without the aid of a suitable delivery system, an inefficient process. Here the interaction of a defined... -
Structural analysis of amino acyl-tRNA-dependent Ligation Reactions in Bacter...
Assembly of the peptidoglycan later of bacterial cell walls is a validated target for anti-bacterial agents: the late transpeptidation and transglycosylation steps are inhibited... -
Competitive interactions in polymer-particle-surfactant blends
Many formulations comprise distinct chemical species that exhibit antagonistic or synergistic interactions that result in unpredictable behaviour. Previous work from our group...
