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Interactions of modified clupeines with Gram-negative model bilayers
Clupeine is isolated from herring and is an example of a protamine, which are cationic antimicrobial peptides occurring in the sperm cells of some fish. Protamines are active... -
Antibody-polysorbate surface interactions
Of concern to the bioprocessing industry is the manner in which polysorbates included in solution formulations of antibodies affect the kinetics and equilibrium state of... -
Quantitative measurement of muonium photochemical reaction kinetics of TIPS-P...
Our first completed photo-musr experiment on 6,13-bis(tri-iso propylsilylethynyl) pentacene (TIPS-Pn) has recently been accepted for publication. We observed a significant... -
Elucidating the Membrane Interaction Mechanism of Chloride Intracellular Chan...
Chloride Intracellular Channels (CLICs) are a family of 6 proteins that have in common a C-terminal CLIC module and chloride-selective ion channel activity. CLIC1 is a 241... -
The effect of phospholipid on the adsorption of HSA at a solid surface
As part of a project concerning the fate of nanoparticles in the body we have been studying the kinetic and competitive (or cooperative) aspects of protein adsorption. HSA is... -
Adsorption of Sodium Polyacrylate onto a-Alumina
In this proposal we investigate the adsorption of the key dispersant additive, sodium polyacrylate, used in colloidal systems using neutron reflection on aluminium oxide, with... -
Phase Behaviour of Colloidal Mixtures Under Shear
There are specific models about the influence of shear on mixtures that are distinctive from dspersions of unifom particles. Understanding the flow behaviour of mixtures of... -
Complex evolution of solution microstructure in LAS / nonionic surfactant mix...
This proposal is part of a broad programme of collaborative research between RAL / Oxford and Unilever, using predominantly scattering techniques to investigate the nature of... -
Copy of: The origins of Biosurfactant self synergy
Biosurfactants are becoming more commonplace in pharmaceuticals, vaccines and other forms of medicines. With the biobased economy growing substantially and pressure to reduce... -
Comparative Interaction Studies of Antimicrobial Agents on Floating Asymmetri...
The outer membrane (OM) of Gram-Negative bacteria (GNB) is an asymmetric structure which contains complex lipids known as lipopolysaccharides (LPSs) on the outer surface. LPSs... -
Interactions of Surfactant Mixtures with Phospholipid Vesicles: the Influence...
Surfactants have been widely used in cosmetics, detergents and pharmaceutical industries. These applications are always accompanied by surfactant-induced skin irritation which... -
Interfacial structures and competitive adsorption of amphiphilic polymers wit...
Foam stability, appearance and functionality is governed by the thin liquid films between foam bubbles. These films are stabilised by surface active molecules (surfactants and... -
Model anionic/non ionic surfactant adsoption at the interface below room temp...
An experiment performed on INTER last year found extreme non ideal mixing between C12E8/SLES3 at the air water interface: this feature became more extreme as the temperature... -
Interfacial layer structure of lipopeptides adsorbed at the air/water interface
Lipopeptide surfactants are a group of interesting biosurfactants due to their natural origin and their high effectiveness at reducing interfacial tension. However, there is a... -
Interaction of keratin with surfactants studied by neutron reflection
This proposal constitutes part of our ongoing study towards understanding how keratin, an important protein component of hair and skin, interacts with ionic surfactants using... -
NR Investigation of Structural Basis Underlying Synergistic Binding of Lipope...
In this part of the proposed work, we wish to explore how antibiotics and antimicrobial peptides interact with model lipid bilayers in the form of a supported lipid bilayer,... -
Electrolyte induced self-assembly of methyl ester sulphonate surfactants
The addition of multivalent counterions (Al3+, Mg2+) induces multilayer adsorption of ionic surfactants at interfaces. It is associated with strong wetting conditions, invoking... -
Generation of 3D-networks by mixing inexpensive HC-polymers, amphiphiles, and...
For the last two decades, many polymers have been tested to increase CO2 viscosity for enhanced oil recovery using CO2 (CO2-EOR). Unfortunately, conventional HC-polymers were... -
Surface adsorption in hydrophobin and hydrophobin / surfactant mixtures
Hydrophobins are secreted fungal proteins and are small lipopeptide biosurfactants. They are strongly surface active and self-assemble at interfaces. Their unique film forming... -
Nanoparticle-surfactant layers at the water-oil interface
The spontaneous selfassembly of nanoparticles (NP) at liquid-liquid interfaces is a phenomenon present in nature and relevant for many applications, such as, emulsion...