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Probing the structure/function relationship of NhaA protein incorporated into...
We propose to perform combined measurements of neutron reflectometry (NR) and impedance spectroscopy (IS) to investigate the structure/function relationship of tethered bilayer... -
Confinement and Lubrication in Liquid Crystal Films
Liquid crystals (LCs) are known to act as good lubricants, however, the reason for this remains unclear. One contributing factor is thought to be the formation of ordered layers... -
Effect of Cholesterol on NHE1 intracellular domain adsorption on lipid bilayers
The Na+/H+ exchanger isoform 1 (NHE1) is a transmembrane protein with the primary function of regulating the pH in the cytosol by exchanging one proton with one Na+ ion. The... -
An In-Situ Study of the Formation of Amyloid Fibrils at Polymer Surfaces Usin...
We propose to study the formation of lateral features during insulin amyloid formation on polymer substrates using off-specular neutron reflectivity. This will be done by... -
Spin Coherent Transport in Organic Spin-Valves
We have recently performed a `proof-of-principle' Low Energy Muon Spin Rotation experiment on an organic spin valve. In an extension to our muon measurements and an attempt to... -
A Surface Chemistry Approach to Microfluidic Capture of T-Cells for On-Body T...
In late 2017, T-cell therapy became the first gene therapy to have been approved by the US FDA and in 2018 approved for use in the UK. From the clinical data presented thus far,... -
Voltage induced actuation - a Kinetics study
This is one of a pair of linked proposals, one for SURF and one for INTER. The voltage response of poly(2-dimethylaminoethyl methacrylate) (PDMAEMA) weak polybase brushes... -
Polarized Neutron Reflectometry study of proximity effects in YBa2Cu3O7-d / L...
To continue with our study on the interaction between superconducting (SC) and ferromagnetic (FM) order parameters we propose to study, by means of Polarized Neutron... -
Purothionins Perturb Bacterial Membrane Function via Ion Channel Formation
Purothionins are a family of cationic cystiene rich plant defence proteins which have been shown to have a wide spectrum of activity due their ability to permeate cellular... -
Adsorption of NHE1 intracellular domain on lipid bilayers
Recently the intracellular domain (ICD ) of the Na+/H+ exchanger isoform 1 (NHE1), is a transmembrane protein, has been identified as an intrinsically disordered protein.... -
Surfactants at the metal-oil interface
The lubrication of surfaces by oils is a key aspect of many academic and industrial problems with significant financial implications. In this experiment we would like to extend... -
Determining the nanostructure of the active layer in thin film organic photov...
Organic photovoltaics are a low cost alternative to existing photovoltaic materials and their efficiency is steadily increasing towards the point where their cost per Watt is... -
NTC2015
This dataset has no description
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Head Group charging and anaesthetic Interaction with Model Bilayers
The mechanism of general anaesthetic action is poorly understood despite their widespread use. It is hoped that investigating the interaction of anaesthetics with lipid bilayers... -
Probing the interfacial wetting of superhydrophobic, lithographically pattern...
Phenomena surrounding the wetting of natural or artificial topographically patterned surfaces are found systems associated with the diverse fields of chemical engineering,... -
Interaction of amino acid based biosurfactants with model lipid bilayers
N-acyl amino acids are surfactants with attractive applications in different technological fields. They are referred to as mild surfactants because they are commonly considered... -
Interfacial structure in self-assembling conjugated polymer photovoltaic devices
The proposal aims to determine the degree of interfacial mixing and roughness at an interface between two conjugated polymers, as part of a broder program to understand how to... -
Phospholipid exchange between tethered bilayers and vesicles
Our objective is to create asymmetric solid surface tethered bilayers (tBLMs) with the the outer leaflet predominately populated by charged phospholipids. tBLMs are produced by... -
Luke Clifton Sample commissioning
This dataset has no description
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Characterising the mechanism of three different corrosion inhibitors on a nic...
This proposal seeks to determine the action of three key classes of corrosion inhibitor for nickel surfaces under acidic environments, in particular the ability of each to...
