103 datasets found

Low molecular weight gelators (LMWG) form hydrogels via self-assembly in water under specific conditions to form long, fibrillar structures. Non-covalent forces interactions...

We have developed an experimental approach using a buried magnetic layer to provide contrast in systems consisting of complex biomolecular layers tethered to gold surfaces. This...

The elusive OMu radical is believed to be formed by muonium reaction with nitrous oxide but has never been directly observed. It would be invisible to transverse-field muon spin...

We have recently performed a measurement of the dipeptide Tryptophanil-Tyrosine (Trp-Tyr) dissolved in deoxygenated water, illuminated by the 4th harmonic of the Nd-YAG laser...

Many biological processes occur at the interface of cells, at the so called cell membrane, such as internalization of biological nanoparticles, including virions, exosomes and...

In this experiment we propose to perform diffraction on isotopically substituted samples of Ca/Yb:ND/H3 and Ca/Yb:15ND3 at two concentrations (8 and 2 MPM) using the new NIMROD...

Cell adhesion and proliferation at the surface of liquids such as oil droplets is a surprising phenomenon as it is typically accepted in the field of bioengineering that cells...

Understanding the fundamental aspects of the surface adsorption and self-assembly of biosurfactant and biosurfactant / conventional surfactant mixtures is a major challenge for...

Block copolymer micelles have been used to encapsulate various chemotherapeutic drugs, which can be delivered to the tumour site using the so-called Enhanced Permeation and...

Short peptide sequences consisting of hydrophobic and hydrophilic amino acid units are capable of self-assembly, leading to interfacial adsorption and solution nano-aggregation....

Endocytosis plays a central role in allowing the selective transport of molecules, via membrane-derived vesicles, into cells. Vesicle formation is controlled by a complex...

Antibiotic resistance is pathogenic bacteria is a major clinical problem. Resistance to all antibiotiotic classes, currentl yin clinical use, has been reported. By contrast, the...

This proposal aims use a novel approach whereby deuterated amyloid peptide fibrils are givenhydrogenated growing ends, and analysed using SANS. The data will enable us to...

Recently, it is reported that the functional nucleosomes, CENP-A nucleosome, H2A.Bbd nucleosome and hexasome, which include variant histone cores, could have flexible and mobile...

This proposal relates to the study on the fundamental level, the hydrophobic interaction A peptides and a lipid monolayer at the oil-water interface. NR will be used to...

Perfluoroalkyl substances (PFASs) are fully fluorinated, stabile, and surface-active compounds. They contain both a hydrophobic fluorinated carbon chain and an ionizable...

Ligand self aggregation is a common problem when studying interactions with bio(macro)molecules. In particular for techniques requiring relatively high ligand concentrations,...

A Unilever proprietary technology has been shown to inhibit biofilm growth and development, and is also found to possess antimicrobial activity, effective both as a...

HSA-NEP is a fusion protein with potential uses in treating Alzheimer’s disease. It consists of Neprilysin, a peptide degrading enzyme, linked to HSA, the most common protein in...

Large multiprotein complexes are the new frontier in structural biology. Individual proteins may be solved by X-ray crystallography but the relationships between subunits and...