151 datasets found

Bacterial membranes contain safety valves called mechanosensitive ion channels, which protect the bacterium from changes in the osmotic pressure of their environment. However,...

Protein-surfactant interactions at an interface play an important role for broad applications in the chemical, dairy, cosmetic and pharmaceutical industries. Rubisco is the most...

Solvents are integral part of the world and so many charge transfer processes take place in a solutions. Unfortunately, not much is known about the microstructure of solvents...

Two days of beamtime on GEM will be used to analyse the structure of the fast lithium-ion conductive phases formed by anion doping the hydrogen storage material LiBH4 with...

Chitosan is a linear polysaccharide that is biocompatible and biodegradable. Chitosan has a number of unique chemical and biological features including its cationic nature and...

Cellulose is produced over tens of billions of tons every year in the world. It is one of the most abundant natural polymer resources. Compared with petroleum-based polymers,...

Conventional ways to administer and deliver drugs have reached its limitations. These methods can be still used for small and simple molecules. However, new carriers have to be...

We propose to explore the morphology of binary mixtures of poly(ethylene oxide), a biomimetic macromolecule, and two different ionic liquids, differing in their hydrogen bonding...

Purothionins and defensins are basic, amphiphilic, cysteine-rich and low molecular weight plant defence proteins. These proteins are active against a broad range of...

Antimicrobial peptides (AMPs), also called host defense peptides, are part of the innate immune system of essentially all species, from bacteria themselves to mammals to protect...

We are developing a new protocol for the preparation of lipid bilayers suitable to host membrane proteins with control on their orientation. Our proposed strategy is based on...

An increasing number of potential drug molecules are extremely water insoluble, limiting their commercialisation as medicines. Solubilisation of drug in surfactant micelles is a...

Many drugs are both poorly water-soluble (hydrophobic) and lipophilic in nature and are therefore incorporated into surfactant micelles and monolayers. As the incorporation of...

Oxidation of lipid membranes is widely known to play a crucial role in many cellular processes and pathological conditions such as apoptosis, inflammation, infection, or sepsis,...

We have engaged in a long term effort to build accurate bio-mimetic systems for complex structural biology studies. Recently, we have found that thiolalkylamidealcohol...

Topological insulators (TIs) are quantum materials having insulating properties in bulk, but display gapless conducting surface states. These conducting surface electronic...

In our recent research at King’s we have shown that significant increases in micellar drug solubilization can be achieved by ‘matching' the hydrophobe of a drug with the...

Biological membranes do not only occur as planar bilayer structures, but bilayers have also been shown to, depending onthe lipid composition, curve into intriguing 3D...

Purothionins and defensins are basic, amphiphilic, cysteine-rich and low molecular weight plant defence proteins. These proteins are active against a broad range of...

Salivary films are (mostly) proteinaceous nm-thick films that form on any type of surface upon exposure to saliva. The role of the pellicle is manifold. Among its functions,...