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Neutron reflectometry of an atopic dermatitis stratum corneum skin model
Atopic dermatitis (AD) is a chronic inflammatory skin condition affecting up to 20% of children and 3% of adults, resulting in significant reduction in quality of life and costs... -
Adsorption of hydrophobin at the oil/water interface
Following our previous study of adsorption of globular lysozyme and BSA, we continue to explore how another globular protein hydrophobin adsorbs at the oil/water interface by... -
Characterising the membrane binding interaction of plant annexin Gh1
Annexins are a ubiquitous group of membrane associated proteins found in animals, plants and fungi. They are linked to wide range of functions including phospholipid... -
The Orientation and Conformation of Synthetic 3-10 Helical Peptides within Su...
This dataset has no description
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Binding behaviour of PAMAMs G5 and G4.5 to zwitterionic and anionic lipid bil...
Polymers are commonly used in drug delivery to create dosage forms that enable delivery of the active ingredient to the site of action within the body. Towards controlled drug... -
Proteins of Different Size and Globular Stability Adsorbed at Oil/Water Inter...
In this work we explore how to use neutron reflection to study protein adsorption at the oil/water interface. Inter is preferred because we have built technical capability on... -
Spray-coating plastic solar cells: New materials & innovative processes for O...
We propose to study a range of new selenium containing lower energy gap organic photovoltaic materials deposited by spray coating using neutron reflectivity. The new materials... -
Temperature Dependence of the Oxidation of Monolayers Under Atmospheric Condi...
The Earth¿s climate is strongly influenced by clouds. The oxidative processing of pollutants in clouds affects cloud droplet size and optical properties, important climatic... -
Insertion of antimicrobial peptides into phospholipid monolayers at air/liqui...
We have designed a series of cationic peptides with different helix repeats that can kill bacteria but remain benign to mammalian host cells. The selectivity to cell types is... -
pH-control of swelling and charge neutralization of thin hydrogel films
Hydrogels are widely used in biomaterials science, much due to excellent protein resistance, and physicochemical properties similar to biological tissue. Charge neutrality is... -
Self-Organisation of Phospholipids on Au Electrodes
This experiment is part of a programme to study the effect of applied electric fields on the structure of biomimetic films formed at Au electrodes, with emphasis on... -
Smectic Wetting at Nematic Surfaces
We have been studying the interaction between nematic liquid crystals and interfaces. It has been found that a surface that anchors the director in a perpendicular orientation... -
Interaction between RNA and lipid monolayers
The objective of the suggested study is to reveal the structure formed when short ssRNA molecules (similar to miRNA) interact with lipid monolayers at the air-water interface.... -
Recreating the specific colicin NRa-LPS interaction in a model bacterial out...
The Gram negative bacterial outer membrane protects the bacterium from external toxins such as antibiotics. This is partially responsible for Gram negative bacteria becoming the... -
Hydrophilic Melt Additive Segregation in Polyolefins
Small molecule additives are used in melt processing, sometimes to lubricate extrusion or to provide bespoke hydrophilic surfaces. Both applications require the additive to... -
Interaction of thermo-responsive deutrated nanogels with lipid monolayer at t...
Drug delivery through skin is an important delivery route. However, the outermost layer of the skin provides a formidable barrier to dermal absorption and penetration for... -
Lipid monolayers at oil/water interfaces at high surface pressure as model bi...
This dataset has no description
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Protein Adsorption at the PDMS Oil/Water Interface
Neutron reflection has been successfully used to measure the conformation of proteins adsorbed at the oil/water interface. However, in several such experiments, hexadecane has... -
Neutron scattering to characterise protein interactions with solid-liquid int...
Objectives of this proposal aim to shed light on how adsorption processes such as protein A chromatography, used to purify biologics, affect protein propensity for aggregation.... -
Introducing the O-antigen into Bacterial Outer Membrane Models
The Gram negative bacterial outer membrane protects the bacterium from external toxins such as antibiotics. This is partially responsible for Gram negative bacteria becoming the...
