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Structural and mechanistic study of nanocapsule / hydrogel composites for dru...
The targeted delivery of non-water soluble drugs for applications such as cancer remains a major challenge. Nanocapsules are new materials that can act as a depot for such drugs... -
Structure and mobility of surfactant additives in PDMS resin
Polysiloxane materials are commonly used in marine coatings due to their inherently low surface energy and flexibility which makes them suitable base materials for foul release... -
Dynamics of amyloid protein fibril elongation using isotope-labelled SANS
This proposal combines small-angle neutron scattering with novel labelling strategies to investigate amyloid protein fibrils. Variations in packing and in the dynamics of... -
SANS study of interaction of iron with alginate
Bowel cancer is the fourth most common cancer in the UK with approximately 41,000 individuals in the UK diagnosed annually. Importantly it is estimated that over half of all... -
Study of creep cavitation in pre-strained creep hourglass test specimens
Studies of creep behaviour in structures that operate at elevated temperatures such as nuclear power plants are important for structural integrity assessments. The effect of... -
Origin of co-nonsolvency, based on the Flory-Huggins interaction parameters o...
Co-solvency and Co-nonsolvency are two extreme phenomena in the field of polymer solution. The former is the phenomenon that a mixture of two nonsolvent forms a good solvent for... -
Exploring the exact morphology and self assembly characteristics of novel pol...
We would like to use SANS to explore the mechanism for preparation and properties of cylindrical micelles. We hope to obtain key information relating to the growth mechanism... -
From polymer molecular architecture to lubrication efficacy and CO2 emission ...
In collaboration with Infineum (a world-leading engine-oil additive company), we propose a SANS study of self-assembly of novel polymethacrylate (PMA) block copolymers as a... -
Bacterial lipoteichoic-acid (LTA) micelles: From molecular self-assembly to m...
Whilst the biological effect of lipoteichoic-acid (LTA) contributing to bacterial infections is widely reported in microbiological and immunological studies, very little is... -
Micelles of highly branched surfactants at the design limit
Results from this experiment will help develop to design 21st century surfactants (better performance with lower environmental consequences) by gaining essential information on... -
Probing the vortex lattice in the iron-based superconductor FeSe
Magnetic field can penetrate a Type-II superconductor to form a vortex lattice (VL) due to the mutual repulsion between the vortices. VL is very important as it contains rich... -
Resolving the DNA interaction of the MexR antibiotics resistance regulatory p...
Acquired multidrug resistance (MDR) in pathogenic microbials is a world-wide threat to human health. Several MarRlike proteins regulate the expression of efflux pumps, which... -
Adsorbtion from nematic mixtures: bulk characterization
The aim is to measure any tendency towards phase separation in a nematic mixture to complement an adsorption study on the same mixture. The base is 4-pentyl 4¿- cyanobiphenyl... -
Investigation of membrane polymer complex using SANS
The interaction between lipid vesicles and macromolecules, like polymers is of intense importance from both theoretical and practical point of view. On one hand lipid vesicles... -
The effect of hydrophobic additives on low molecular weight gels
Low molecular weight gels are the result of the self-assembly of small molecules into fibres. These entangle to entrap the solvent. When the solvent is water, these are called... -
SANS Contrast Matching Studies of Radiation-grafted Anion-exchange Membranes
We request two days beam time on SANS2D for the study of radiation-grafted anion-exchange membranes, both dry and hydrated under different ratios of D2O/H2O. These materials... -
Interaction of a pH-sensitive Polymer with a Model Lipid Membrane in the Form...
This SANS experiment was proposed by 4 PhD students from 3 different institutions in a Marie-Curie Training Network. They are all in the second year of their PhD and their... -
Understanding elevated temperature and creep properties of a novel maraging s...
Producing a steel alloy that has both high and low temperature capabilities is non-trivial. However, recently a novel maraging steel has been developed that has shown excellent... -
Can SANS confirm whether dimensions from microscopy of dried gels are represe...
Characterisation of structures formed within hydrogels is an important part of understanding their properties and how they can be used in real world applications. The real space... -
Anion effects on self-assembly in deep eutectic solvents.
Deep Eutectic Solvents (DES) are mixtures of an organic salt with a hydrogen bond donor that form strong interactions which hinder crystallisation. DES share many features with...
