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Calcium and pH induced changes in silk solutions
Spider silks are known to have outstanding mechanical properties yet there is still much unknown about how the initial structure, storage and transformation of the silk proteins... -
Adsorption of nanodics (stabilised by sytrene-maleic anhydride derived copoly...
Nanodiscs are self-assembled structures that consist of a bilayer of phospholipids controlled in diameter by a polymer or protein belt. We have already shown that such discs... -
Interactions of artificial membrane binding proteins with model membranes
This dataset has no description
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Domain patterning in bicontinuous cubic lipid phases
Dynamic microdomains, resulting from lateral lipid inhomogeneity and patterning within biological membranes, have been implicated in a wide range of critical cellular processes... -
Lipid-polymer nanodiscs stabilized with novel sytrene-maleic anhydride derive...
Polymer stabilized lipid nanodiscs offer enormous potential as tools for enabling membrane protein structural studies & biophysics. Previously we studied nanodisc formation... -
Using SERGIS to characterise monolayer buckling on the approach to collapse
Thin films just one or a few molecules thick can play an important role in controlling many important phenomena. This includes the lipid monolayers that coat the surface of our... -
Lipodepsipeptides and Brown Blotch Disease in Mushrooms (i) Effect of biogeni...
Tolaasin is a lipodepsipeptide (lipo = hydrophobic side chain, depsipeptide is an amino acid ring closed in a particular way) produced by strains of Pseudomonas tolaasii, and it... -
Structural studies of Staufen1 in complex with Upf1, a crucial assembly in ge...
Gene expression is regulated during both the synthesis and the decay of mRNAs. Various pathways of cytoplasmic mRNA decay exist. These include ARE-mediated decay, miRNA-Mediated... -
Reconstitution of human dihydroorotate dehydrogenase into lipid-detergent mic...
Human dihydroorotate dehydrogenase (DHODH) is an integral membrane protein found in mitochondria involved in the biosynthesis of pyrimidines. DHODH oxidizes dihydroorotate with... -
Neutron Reflection Studies on Adsorption of Lauroyl-L-Carnitine (C12-L-Caniti...
Acyl L-Carnitines are a group of novel surfactants with attractive physical and biological properties associated with their head group charge features. This work proposes to use... -
Studying the Hydration Properties of Green Hybrid Nanocomposite Cellulose Films
We are investigating innovative hybrid organic/inorganic multilayered films comprising alternated layers of cellulose nanocrystals (CNCs) and Gibbsite platelets (GW). CNCs are... -
Electrochemically Growing Hydrogels to Control Stiffness
At high pH many low molecular weight gelators (LMWG) are dispersed in solution. When a trigger is applied to lower the pH the gelator molecules self-assemble into one... -
The Interaction of Wild-type and Mutant Puroindoline B with Model Bacterial M...
Our recent solid-state NMR and EPR studies have identified differences in the lipid binding behaviour of wild-type and mutant puroindoline B proteins. These studies have shown... -
SANS2D The structure of shear-compliant and shear-resistant mucin and mucus
This collaborative study with the molecular physiology group from Newcastle is part this large EU funded FP7 project which aim is to develop new nanoparticulate drug delivery... -
SESANS investigation of structural colour in polar bear hair
Structural colour arises not from dyes or pigments, but from light scattering off of the inner geometry of the material itself. This offers greater stability than standard... -
Investigation of the structure and formation of alphasynuclein-lipid co-aggre...
Alpha-synuclein is tan intrinsically disordered protein whose aggregates are an hallmark of Parkinson's Disease (PD). Alpha-syn is known to associate with lipid membranes and... -
GISANS directed to study lipid bilayer structures on nanowire arrays
Nanowires are increasingly being used in life science to interact with living cells, for example as nanometer probes. The interaction between the cell membrane, i.e. a lipid... -
Effect of shear and adsorbing polymers on cellulose micro-fibrils
This dataset has no description
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Role of Antifreeze Glycoproteins (AFGPs) in Preventing Ice-formation
Antifreeze glycoproteins (AFGPs) are an important biological complex and a novel set of proteins that can prohibit the formation of ice. The AFGPs can be extracted from the... -
Membrane interactions of virus-like silica nanoparticles as antimicrobial pep...
As a result of an increasing number of bacteria developing resistance against antibiotics, antimicrobial peptides (AMPs) are currently attracting significant interest. However,...
