Lipodepsipeptides and Brown Blotch Disease in Mushrooms (i) Effect of biogenic amines

DOI

Tolaasin is a lipodepsipeptide (lipo = hydrophobic side chain, depsipeptide is an amino acid ring closed in a particular way) produced by strains of Pseudomonas tolaasii, and it causes Brown Blotch disease in mushrooms. This is a major problem in commercial mushroom growing. Tolaasin is detected by the formation of a "white line" when it comes into contact with the lipodepsipeptides, WLIP (White Line Inducing Peptide) created by Pseudomonas reactans. WLIP is evidently antagonistic to tolaasin but the mechanism is not understood. White line formation is enhanced by the biogenic amine, octopamine. Preliminary reflection experiments confirm a strong specific interaction of octopamine and WLIP. This seems to require an unfolding of the known solid state structure of WLIP and we propose to determine the layer structure using reflectometry and part deuterated WLIP.

Identifier
DOI https://doi.org/10.5286/ISIS.E.81735343
Metadata Access https://icatisis.esc.rl.ac.uk/oaipmh/request?verb=GetRecord&metadataPrefix=oai_datacite&identifier=oai:icatisis.esc.rl.ac.uk:inv/81735343
Provenance
Creator Dr Souvik Kusari; Dr Peixun Li; Professor Jeffery Penfold; Professor Gail Preston; Dr Bob Thomas; Mr Marcel Bach Pages; Dr Rebecca Welbourn
Publisher ISIS Neutron and Muon Source
Publication Year 2019
Rights CC-BY Attribution 4.0 International; https://creativecommons.org/licenses/by/4.0/
OpenAccess true
Contact isisdata(at)stfc.ac.uk
Representation
Resource Type Dataset
Discipline Biology; Biomaterials; Engineering Sciences; Life Sciences; Materials Science; Materials Science and Engineering
Temporal Coverage Begin 2016-07-07T08:00:00Z
Temporal Coverage End 2016-07-10T08:00:00Z