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Bulk interactions of surfactant molecules in aqueous particle suspensions
Surfactants represent an important class of compounds owing to their ability to readily locate at interfaces, be it airliquid, liquidliquid or solidliquid. As such,... -
SANS Study of pH-Triggered Behaviour in Pluronic-Flurbiprofen Solutions: In v...
Hydrophobic drug encapsulation is one of the widely used strategies to overcome the poor adsorption and bioavailability of these drugs in vivo. Water-soluble amphiphilic... -
Polymer-Lipid Nanodisc Self-assembly Processes Using Stop Flow
Polymer stabilized lipid nanodiscs offer enormous potential as tools for enabling membrane protein structural studies & biophysics. Polymer stabilized lipid bilayer discs... -
Concentrated emulsions as proxy CO2 thickeners
The proposal aims to explore the oil-in-water (brine) high internal phase emulsion systems (HIPEs) formed by nonylphenol ethoxylate surfactants using contrast variation SANS... -
Effect of drug on the micelles formed by ionic surfactants
The aim of the study is to use SANS in combination with contrast variation to determine the effect of solubilising the lipophilic drug, testosterone propionate, in micelles... -
Rapid microfluidic phase mapping of SDS:water:butanol
Sodium dodecyl sulfate (SDS) is an anionic surfactant, extensively employed in cosmetics and personal care, as well as in pharmaceuticals and food products. Surfactants are... -
Dynamical process of helical-biskyrmion transformation of hexagonal magnet Mn...
Magnetic skyrmions are vortex-like, magnetic-spin objects that were lately discovered in bulk chiral magnetic materials. Recently, we discovered super stable magnetic... -
Novel protophane and cyclophane surfactants
Novel Gemini surfactants (protophanes and cyclophanes) have been synthesised as model biological anion receptors, and their critical micelle concentrations determined by surface... -
Molecular Collapse and Conformation of Low Molecular Mass Polyacrylic Acid an...
There is conflicting information about properties of polycrylic acid and its behaviour in aqueous solution. This proposal for an investigation by SANS that is directed at... -
Polymer-Lipid Nanodisc Self-assembly Processes Using Stop Flow
Polymer stabilized lipid nanodiscs offer enormous potential as tools for enabling membrane protein structural studies & biophysics. Polymer stabilized lipid bilayer discs... -
Investigating the effect of nanoparticles on PBI self assembly
The generation of hydrogen from water using light could be a method of providing a clean fuel, which is clearly important for our growing energy needs. We are using perylene... -
Perfluorocarbon-loaded polymeric nanoparticles with multiple perfluorocarbon ...
Ultrasound is a very attractive and patient-friendly imaging technique, as it is easy to use, fast and non-invasive. Nevertheless, its use is severely limited by the low... -
How do polymeric de-emulsifiers work? Contrast variation studies with model w...
The project is to understand fundamental structure-performance relationships of chemical demulsifiers in water-in-crude oil (w/o) systems. In particular, to understand how... -
Aggregation behaviour in solution of cationic conjugated polymers and oligomers
In the proposed experiments we extend previous work on characterization of aggregates formed by cationic conjugated polymers and oligomers in water. Particular emphasis will be... -
Molecular Mechanistic Processes of Complexation between DNA and Cationic Copo...
It is difficult for the naked external gene to become internalized due to its similar charge to the extracellular membrane surface. Various cationic copolymers and cationic... -
Structural analysis of amino acyl-tRNA-dependent Ligation Reactions in Bacter...
Assembly of the peptidoglycan later of bacterial cell walls is a validated target for anti-bacterial agents: the late transpeptidation and transglycosylation steps are inhibited... -
The action of membrane lytic compounds on model membranes.
The study of antifungal and antibacterial action is of great interest and there are still many unknowns concerning the action of membrane lytic materials, and the way that... -
Unravelling the solution structures and stability of industrially-important a...
The glycosylation of glycoproteins is a major determinant of their stability, and glycans also affect their aggregatibility (precipitation). An understanding of this is... -
Probing the bulk morphology of fullerene-free organic solar cell blends using...
The aim of this project is to develop an understanding of the relationships between the processing, nanoscale structure and device performance of bulk heterojunction,... -
Solvent-induced curvature of micelles
The purpose is to follow a structural evolution as water soluble (normal curvature) micelles are gradually transformed into oil soluble (reversed curvature) aggregates. Although...
