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Oxidation of gram-negative cell-wall proxy with OH radicals - kinetics and me...
Hydroxyl radicals may be used as disinfection agent in the advanced oxidation processes or tertiary treatment of waste and occasionally drinking water. In this exploratory work,... -
Understanding light-induced changes to the miscibility of polymer/fullerene s...
Polymer/fullerene blends represent the most common form of organic solar cell. This proposal forms part of a wider effort in which our motivation is to complement solar cell... -
Structural evidence of lipopolysaccharides functioning as receptors in antimi...
The global increase of bacterial resistance to antibiotics has led to increasing interest in research focusing on the development and characterization of new antimicrobial... -
Membrane-stacking Properties of Mutant Myelin Proteins
Myelin is the multilamellar structure that ensheaths axons and accelerates nervous impulses in the nervous system. The fine structure of myelin remains to be further... -
Antibiotic Interactions with models of the Gram negative bacterial outer memb...
Gram-negative bacteria, which cause a variety of diseases including meningitis, plague, sepsis and food poisoning, are becoming increasingly antibiotic resistant. One reason is... -
The structure and orientation of the Bam complex in the Gram-negative outer m...
The proteins of the outer membrane of Gram-negative bacteria are critical for bacterialsurvival, from providing basic physiological functions, to aiding virulence and... -
The structure of pharmaceuticals in aqueous solution: towards better drug sol...
The pharmaceutical industry has been described as being 'in a period of crisis' as the number of drug approvals relative to most major pharmaceutical companies Research and... -
Neutron reflectivity study of phase separation in polymer-drug thin films
Nearly 40% of new chemical entries are poorly water-soluble. Drug encapsulation into water-soluble polymers is an active research area owing to the ability of improving drug... -
Dynamic P3HT Nanowire Growth in Solution (Sans2d)
We propose to use SANS to probe the self organised formation of P3HT nanowires in a solution of deuterated chlorobenzene over a 48 hr period in order to better understand the... -
Neutron reflectivity of water soluble conjugated polymer/surfactant films
Water-soluble conjugated polymers (WSCP) are an important class of materials which have received great attention as active materials in optoelectronic devices and in biosensing.... -
Self-assembly of beta-casein and beta-casein / hydrophobin mixtures
Hydrophobins, hfb2, are secreted fungal proteins in the form of a small lipopeptide. They are strongly surface active and self-assemble in solution and at interfaces. They have... -
Structure of Confined Albumin Layers
In the context of a project in collaboration with ISIS that focuses on structural studies under mechanical confinement, with a specific focus on biological lubricants, the... -
Modelling the Intracellular Lipid Shuttling Mechanism of Non Specific Lipid T...
Previously we have examined the interaction of barley non-specific lipid transfer protein (nsLTP1) with OTS and lipid monolayers at the solid/liquid interface. Examining the... -
Magnetic contrast NR to resolve MscL opening under PXG challenge
In bacteria, mechanosensitive ion channels such as MscL protect cells against osmotic shock, but, as with all ion channels, they have the potential to act as an Achilles heel,... -
Lipid exchange between high density lipoprotein (HDL) and model phosphatidylc...
Lipoproteins are the main carriers of lipids in the body. HDL is believed to favor cholesterol removal and decrease the risk to develop atherosclerosis and related... -
CRISP ACCESS FOR NON-COLLINEAR MAGNETISM
The Superconducting Ferromagnetic Metamaterials (SFM) consortium -
A study of the role of divalent cations in the stability of smooth LPS in out...
The Outer Membrane (OM) is found in bacteria which cause plague, cholera & Legionnaires disease. It is important as; a barrier to antibiotics & the site of... -
Interfacial layer structure of designed lipopeptides at the solid/water inter...
Lipopeptide surfactants are a group of interesting biosurfactants due to their natural origin and their high effectiveness at reducing interfacial tension. However, there is a... -
Neutron Diffraction Studies of Vanadium Sulfate Cathode Materials
Vanadium based compounds have attracted considerable interest as positive electrode materials for Li ion batteries. This is due to vanadiums ability to display a range of... -
Model Amphiphilic Deep Eutectic Liquids
Deep eutectic liquids (DELs) - mixtures of high melting-point solids that form stable liquids near room temperature ¿ have recently emerged as a new class of novel solvents with...