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The effect of polymer therapeutics on the structure of mucin solutions toward...
Progress in the development of nano-sized hybrid therapeutics and nano-sized drug delivery systems - "nanomedicines" - over the last decade has been remarkable. One key... -
Formulating polymer solutions to stabilise polymeric foams
Polyurethane foams (PUF) are commonly prepared by mixing Pluronic type copolymers and isocyanate reactive monomers in the presence of additives e.g. catalysts, blowing agents... -
On the Mechanism of Self-Assembling Chiral Gelators
Organogelators are small molecules that self-associate into extensive network structures. Our interest lies in a homologous series of such gelators, the... -
The impact of added particles and surfactant on HEUR thickener solution struc...
Paints are typical formulated products. The paint consists of many different components - pigments, thickeners, surfactants - each of which has a specific function. The physical... -
SANS2D The structure of shear-compliant and shear-resistant mucin and mucus
This collaborative study with the molecular physiology group from Newcastle is part this large EU funded FP7 project which aim is to develop new nanoparticulate drug delivery... -
SANS from photoconductive hydrogel mixtures and their gelators.
Hydrogels are formed from a self?assembled network of fibres made up of small molecules (gelators) trap and hold water at just 1% by weight, or less, from the solution they are... -
Rheo-SANS study of peptide gels
Low molecular weight gelators (LMWG) form hydrogels via self-assembly in water under specific conditions to form long, fibrillar structures. Non-covalent forces interactions... -
Phase separation of poly(ethylene glycol) and of poly(propylene glycol) in mi...
Phase behaviour studies have identified hydrogen bonding as a key aspect in polymer solubility in fluorinated liquids, both in terms of solute-solvent and solute-solute... -
The effect of particles on the structure of mucin ¿understanding the challeng...
Progress in the development of nano-sized hybrid therapeutics and nano-sized drug delivery systems - "nanomedicines" - over the last decade has been remarkable. One key... -
Investigating a Dextrin-Phospholipase A2 Conjugate as a Trigger for Polymer E...
Recent research has demonstrated the potential of nanosized delivery systems for routine use in many diseases, eg cancer, viral diseases and rheumatoid arthritis [1,2], due to... -
Emission Enhancing Micelles and Microemulsions for the Analytical Sciences
Nuclear power has played an important role in Britain¿s history and is set to play an equally important role in its future. We have recently established a network involving... -
Structural characterization of a series of polymer-protein conjugates for chr...
Polymer-protein conjugates have been designed to deliver an appropriate target growth factor to promote a more rapid healing of chronic wounds, an incredibly important area for... -
The effects of molecular weight on the structure of non-covalent polymer ther...
Polymer therapeutic describes polymeric drugs, polymer-drug conjugates, polymer-protein conjugates, polymeric micelles to which drug is covalently bound, and multicomponent... -
Competitive and synergistic interactions in gel formation
The interactions of small molecules with Pluronic copolymers are of relevance to their numerous pharmaceutical, domestic, technological and industrial applications. Whereas the... -
Metallosurfactant Enhanced 90Sr Determination by Improved Liquid Scintillatio...
Nuclear power at present is the only viable option for long-term power generation in the UK and as such the easy incorporation of the fission product 90Sr into the biosphere... -
Understanding the permeation of candidate drug delivery particles through the...
This collaborative study with the chemical engineering groups from University of Innsbruck, Austria and Aristotle University of Thessaloniki, Greece is part of this large EU... -
Investigation of the micellar aggregates in low molecular weight gelators
We have been investigating dipeptide-based low molecular weight gelators. Here, on lowering the pH from 12 to 4, a self-supporting gel is formed. Gels are formed by the... -
On the peculiarities of the structure of particle stabilised foams
Many formulated products pass through or end up as foams, comprising immiscible millimeter sized bubbles dispersed into an aqueous continuous phase. Frequently, surfactants or... -
Understanding the permeation of candidate drug delivery particles through the...
This collaborative study with the chemical engineering groups from University of Innsbruck, Austria and Aristotle University of Thessaloniki, Greece is part of this large EU... -
Metallomicroemulsions - a new class of supramolecularly organised metal ions
Incorporation of d- or f-block metals into ligand systems that renders a metal complex surface active or drives its partitioning into surfactant phases enables the localisation...
