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A neutron reflectometry study of the interaction of octanohydroxamate with iron
The interaction of alkyl hydroxamate with iron is of interest in mineral flotation science, corrosion control and also as a model for microbial siderophore chemistry. Long chain... -
CLIC1 Protein Interactions with Model Cell Monlayer Membranes
This dataset has no description
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Function and Structure of Reconstituted Neurotransmitters in biomembranes
Neurotransmitter transporters recognize biogenic amines dopamine, serotonin, noradrenalin and γ-amino butyric acid (GABA). They all belong to the family of... -
Formation of asymmetric free-standing bilayers with lipopolysaccharide in the...
We have recently improved the stability and coverage of free standing bilayers by the use of a supporting thiolipid layer on gold. The system has been investigated on POLREF and... -
Structural study on the 3D arrangement of (hexa-acyl) lipid A in lipid membrane
This study will focus on the structural investigations of the bilayers formed on silicon substrates in which the outer leaf consists of DOPE/LPS mixtures. We aim is to achieve... -
The solution structure of the OmpF¿Colicin N complex in neutral detergent by ...
Gram negative bacteria cause a wide range of diseases. Colicins are protein toxins capable of penetrating the outer membrane barrier and killing the bacteria. Thus they... -
Structure of bacterial outer membranes after attack by primary immunity proteins
We have now succeeded in getting consistently high-quality data from our unique model of the bacterial outer membrane. This involves achieving a highly asymmetric bilayer with... -
The solution structure of the OmpF¿Colicin N complex in neutral detergent by ...
Gram negative bacteria cause a wide range of diseases including meningitis, bubonic plague, gonorrhoea, diarrhoea, Legionnaires' disease and cholera. Their outer membrane... -
Comparative Interaction Studies of Antimicrobial Agents on Bacterial Membrane...
The outer membrane (OM) of Gram-Negative bacteria (GNB) is an asymmetric structure which contains complex lipids known as lipopolysaccharides (LPSs) on the outer surface. LPSs... -
A model of the bacterial outer membrane containing both Outer Membrane Protei...
We have recently improved the stability and coverage of free standing bilayers (FSB) by the use of a supporting thiolipid layer on gold. The system has been investigated on... -
Floating Bilayer Mimics of the Gram Negative Bacterial Outer Membrane
The gram-negative bacterial membrane is of extreme medical importance. The two main lipid components of the outer membrane are lipopolysaccharides (LPS's) and DOPE. We will... -
A complex model of the bacterial outer membrane containing oriented proteins ...
The Outer Membrane (OM) is found in bacteria which cause plague, cholera & Legionnaire?s disease. It is important as; a barrier to antibiotics & the site of... -
Comparative Interaction Studies of Antimicrobial Agents on Floating Asymmetri...
The outer membrane (OM) of Gram-Negative bacteria (GNB) is an asymmetric structure which contains complex lipids known as lipopolysaccharides (LPSs) on the outer surface. LPSs... -
Antibiotic binding to a bacterial outer membrane model containing oriented pr...
The Outer Membranes (OM) is a feature of many pathogenic bacteria. It is important as a barrier to antibiotics & the site of human-bacteria interaction. However bacteria are... -
Stability and protein binding interactions of a free standing model bacterial...
We recently improved free standing bilayers using a thiolipid layer on gold which also permits magnetic contrast reflectometry. One use for this system is to contribute to our... -
Floating Bilayers Deposited on Au / Fe Surfaces
There is currly great interest in the use of neutron reflection to study model bilayers. We have produced a model membrane system that is strongly associated with the substrate,... -
Application of direct inversion to magnetic contrast datasets.
We have developed an experimental approach using a buried magnetic layer to provide contrast in systems consisting of complex biomolecular layers tethered to gold surfaces. This... -
Orientation of an Antimicrobial Peptide in Eukaryotic and Prokaryotic Membranes.
Antimicrobial peptides are small, usually alpha-helical peptides that kill cells by disrupting the cell membrane. Recently, we have been studying a simple 'designed'... -
Detailed Structure of Phospholipid Bilayers from Multiple Contrast Neutron Re...
Floating bilayers are supported phospholipid membranes, which are minimally constrained by the influence of the substrate, and therefore considered to be more realistic than... -
Interaction of Antimicrobial Silver Nanoparticles with Eukaryotic and Prokary...
Silver nanoparticles have been shown to have strong antimicrobial effects against many organisms, including those resistant to conventional antibiotics. However, the exact...
