Water dynamics plays a vital role in biochemical processes in a living organism. Intracellular water structure and dynamics are known to be changed by the presence of biomolecules or extrinsic entities (e.g. drugs), while in turn water is prone to disturb the conformation and function of biomolecules. Disruption of the coherent structure of cellular water by even very subtle stimuli is expected to have a significant cost at the functional level and may even induce pathology.The present study aims at extending this concept to the activity of pharmacological agents. Upon a successful exploratory experiment (OSIRIS/RB1400034), the QENS technique will be used to probe the effect of an anticancer drug (cisplatin) on water dynamics in human cancer cells. This is an innovative way of tackling the drug´s pharmacodynamics leading to an improved understanding of its in vivo mode of action.