-
PYY antifungal properties
Looking at the microbial population in lumen and colon samples of PYY KO and WT mice. -
Hydrolysis rates of bio-based polymers
Bio-degradation assays were performed for bio-based polymers under environmental conditions with controlled temperature and pH using pH Stat titration. Suspensions of PLA and... -
Effect of formulation method and lipid composition on liposome lamellarity
Liposomes are vesicles comprising a phospholipid membrane bilayer around an aqueous core. They are well-established in the fields of drug delivery and diagnostics. To translate... -
Self-assembly of lipid and triblock copolymer-based amphiphiles for drug deli...
Soft self-assembled structures have been extensively used as drug nanocarriers. Their building blocks, naturally occurring and synthetic amphiphiles (lipids or block... -
Polymer-Lipid Nanodisc Self-assembly Processes Using Stop Flow
Polymer stabilized lipid nanodiscs offer enormous potential as tools for enabling membrane protein structural studies & biophysics. Polymer stabilized lipid bilayer discs... -
Polymer-Lipid Nanodisc Self-assembly Processes Using Stop Flow
Polymer stabilized lipid nanodiscs offer enormous potential as tools for enabling membrane protein structural studies & biophysics. Polymer stabilized lipid bilayer discs... -
Outer membrane mimics using novel thiol-PC
We have recently shown that dense monolayers of PC can be assembled on gold surfaces using a new omega thiol PC from Avanti. This has two advantages over our previous methods.... -
Investigating liposome sensitivity towards phospholipases for applications in...
Liposomes are lipid-based, water-filled vesicles with wide-ranging applications in diagnostics and drug delivery. Phospholipases (PLs) are enzymes that cleave specific bonds in... -
DRUG EFFECTS ON INTRACELLULAR WATER DYNAMICS: CISPLATIN IN HUMAN CANCER CELLS
Water dynamics plays a vital role in biochemical processes in a living organism. Intracellular water structure and dynamics are known to be changed by the presence of... -
Nanodiscs films at the air-water interface
Nanodiscs are self assembled complexes of phospholipids and a class of amphipathic helical proteins termed membrane scaffold proteins . The proteins and lipids self-assemble... -
Engineered anisotropic liposomes for drug delivery
It is well established that the anisotropy of nanoparticles has a dominant effect on increasing their uptake by cells. However, the advantage of anisotropy for cell penetration... -
Impact of Protein Nanosheet Structure on Nanoscale Toughness
Cell adhesion and proliferation at the surface of liquids such as oil droplets is a surprising phenomenon as it is typically accepted in the field of bioengineering that cells... -
Surfactant Modified Salivary Pellicles
Salivary films are (mostly) proteinaceous nm-thick films that form on any type of surface upon exposure to saliva. The role of the pellicle is manifold. Among its functions,... -
The effect of fatty acids on the adsorption of HSA at the silica water interface
The primary biological function of albumins is to be fatty acid carriers. The complexation of fatty acids to the albumin is expected to have a strong effect on its adsorption... -
Co-adsorption and competitive adsorption of eggshell membrane polypeptide aga...
In this work we explore how to use neutron reflection to study the interfacial adsorption from a natural eggshell membrane polypeptide at the oil/water interface. We will then... -
Manipulating surface adsorption of SLES surfactants using temperature
Although surfactant detergency is well understood above 30 C, actions of surfactants below 30 C are not well established. In the era of energy saving and environment caring, we... -
Investigation on the self-assembling of amphiphilic peptides
This dataset has no description
-
Competitive adsorption in hydrophobin-surfactant mixtures
Hydrophobins are small compact secreted fungal proteins which are strongly surface active and adhere to both hydrophobic and hydrophilic surfaces. Their strong surface activity... -
Effect of End Group on RAFT-Polymers for Lipid Nanodisc Stabilisation
Polymer stabilized lipid nanodiscs offer enormous potential as tools for enabling membrane protein structural studies & biophysics. Previously we studied discs formed using... -
Interactions of de Novo Designed Antimicrobial Lipopeptides with Model Leafle...
In this work, we propose to exploit the unique capability of neutron reflection (NR) to study the structural changes of multi-component lipid monolayer models mimicking...
