Variability of the continuum, H{beta}, H{gamma} and HeII(4686{AA}) fluxes of the Seyfert I galaxy Mrk 509 is studied using spectra obtained on the 2.6-m telescope of the Crimean Astrophysical observatory from 1971-1993. All the measurements of fluxes are in the relative units normalized to the flux of OIII taken equal to 100. The flux in the line OIII is estimated in the interval of (5.7-7.6)10^-13^erg/cm^2^/s=(5.7-7.6)10^-16^W/m2. The variability amplitude in the continuum is higher than in the hydrogen lines.