ABlab_IFNLGutRestitution_IonTorrent_bulkRNA-seq

Dataset

DOI

To determine the transcriptional programs initiated by IFN-λ to delay tissue restitution, we isolated intestinal crypts from the small intestine of VilCREIfnlr1fl/fl mice or WT littermates that have been irradiated and performed targeted transcriptomics analysis

WT mice and VilCREIfnlr1fl/fl mice received 11 Gy ionizing radiation, with lead shielding of the upper body. Targeted transcriptomics was performed on freshly isolated small intestinal crypts. Barcoded libraries were prepared using the Ion AmpliSeq Transcriptome Mouse Gene Expression Panel, Chef-Ready Kit (A36412; Thermo Scientific)

See description of the dataset in https://github.com/CIML-bioinformatic/ABlab_IFNLGutRestitution

Identifier
DOI	https://doi.org/10.57745/MB71AU
Related Identifier	IsCitedBy https://doi.org/10.1016/j.cell.2024.10.010
Metadata Access	https://entrepot.recherche.data.gouv.fr/oai?verb=GetRecord&metadataPrefix=oai_datacite&identifier=doi:10.57745/MB71AU

Provenance
Creator	JENA, Kautilya K ; MAMBU, Julien ; BOEHMER, Daniel ; SPOSITO, Benedetta (ORCID: 0000-0001-9507-187X); MILLET, Virginie ; DE SOUSA CASAL, Joshua ; MUENDLEIN, Hayley ; SPREAFICO, Roberto ; FENOUIL, Romain ; SPINELLI, Lionel ; WURBEL, Sarah ; RIQUIER, Chloé ; GALLAND, Franck ; NAQUET, Philippe; CHASSON, Lionel; ELKINS, Megan ; MITSIALIS, Vanessa ; KETELUT-CARNEIRO, Natalia ; BUGDA GWILT, Katlynn ; THIAGARAJAH, Jay (ORCID: 0000-0002-1437-325X); RUAN, Hai-Bin ; LIN, Zhaoyu ; LIEN, Egil ; SHAO, Feng ; CHOU, Janet ; POLTORAK, Alexander ; ORDOVAS-MONTANES, Jose ; FITZGERALD, Kate (ORCID: 0000-0003-3175-609X); SNAPPER, Scott ; BROGGI, Achille ; ZANONI, Ivan
Publisher	Recherche Data Gouv
Contributor	SPINELLI, Lionel; Centre d'Immunologie de Marseille-Luminy; Aix-Marseille Université; Centre National de Recherche Scientifique; Institut National de la Santé et de la Recherche Médicale
Publication Year	2025
Funding Reference	NIH ; Lloyd J. Old STAR Program CRI3888 ; Pathogenesis of Infectious Disease Award from the Burroughs Wellcome Fund ; Aix Marseille Université-A*Midex AMX-20-CE-01 ; FRM amorçage de jeunes equipes AJE202010012468 ; ANR-JCJC grant ‘‘INTERMICI’’ ANR-21- CE15-0022 ; French National Research Agency ‘‘Investments for the Future’’ ANR-10-INBS-04 ; Deutsche Forschungsgemein-schaft 515356385 ; NIH AI146855 ; NIH AI181309
Rights	etalab 2.0; info:eu-repo/semantics/openAccess; https://spdx.org/licenses/etalab-2.0.html
OpenAccess	true
Contact	SPINELLI, Lionel (Aix Marseille Université)

Representation
Resource Type	Dataset
Format	text/html; text/plain; application/pdf; text/comma-separated-values; type/x-r-syntax; application/octet-stream
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Version	1.0
Discipline	Life Sciences; Immunology; Medicine; Microbiology, Virology and Immunology
Spatial Coverage	Marseille, France