Saccharomyces eubayanus CDFM21L.1 and maltotriose heterosis

Here, we investigated if and how the genomes of Asian S. eubayanus strains could have contributed to maltotriose utilization by generating chromosome-level genome assemblies using Oxford Nanopore Technology (ONT) long-read sequencing. Since the Asian strains were unable to utilize maltotriose, we functionally characterized the assembled MAL genes and identified genetic determinants limiting maltotriose utilization. Finally, we generated hybrids between an Asian S. eubayanus strain and a maltotriose-deficient ale S. cerevisiae strain to investigate the heredity of maltotriose utilization. We analyzed the implications of our results for the role and origin of SeAGT1 in S. pastorianus and for the potential of hybridization to enable maltotriose consumption in novel S. pastorianus hybrids.

Identifier
Source https://data.blue-cloud.org/search-details?step=~012C4C875DD6878B490BA5556AE1C081C1BC5D187CE
Metadata Access https://data.blue-cloud.org/api/collections/C4C875DD6878B490BA5556AE1C081C1BC5D187CE
Provenance
Instrument Illumina HiSeq 2500; Illumina MiSeq; MinION; ILLUMINA; OXFORD_NANOPORE
Publisher Blue-Cloud Data Discovery & Access service; ELIXIR-ENA
Publication Year 2024
OpenAccess true
Contact blue-cloud-support(at)maris.nl
Representation
Discipline Marine Science
Temporal Coverage Begin 2014-01-01T00:00:00Z
Temporal Coverage End 2018-01-01T00:00:00Z