Water is crucial for the functioning of proteins. There has been substantial work to study the effect of water on protein dynamics, structure and function. However, how protein structure affects the dynamics of water, especially the diffusive character of water, is not thoroughly explored. Our earlier work on perdeuterated GFP showed that the hydration water molecules perform a sub-diffusive motion, which is quantitatively confirmed by our molecular dynamics simulation. However, our further molecular dynamics simulation found that the sub-diffusive nature of hydration water and the detailed diffusion rule are universal and independent on the structure of the associated protein. To support this simulation-derived conclusion, we require dynamic neutron scattering data on another perdeuterated protein, which is P450 as proposed here, and it is the essential goal of this proposal.