Replication Data for: Fibrillar adhesion dynamics govern the timescales of nuclear mechano-response via the vimentin cytoskeleton

Dataset

DOI

This data set includes all the source data corresponding to the each figure published in the paper entitled “Fibrillar adhesion dynamics govern the timescales of nuclear mechano-response via the vimentin cytoskeleton”. These data demonstrate that the formation of fibrillar adhesions and remodelling of the extracellular matrix protein fibronectin, delays the timescales at which the cell nucleus responds to changes in the mechanical environment. Mechanistically, this is mediated by the anchoring of the vimentin cytoskeleton to fibrillar adhesions by plectin-1f.

Identifier
DOI	https://doi.org/10.34810/DATA2992
Related Identifier	IsSupplementTo https://doi.org/10.1038/s41563-026-02590-x
Metadata Access	https://dataverse.csuc.cat/oai?verb=GetRecord&metadataPrefix=oai_datacite&identifier=doi:10.34810/DATA2992

Provenance
Creator	beedle, amy ; Sharma, Vivek ; Oliver-De La Cruz, Jorge ; Jaganathan, Anuja ; Albajar Sigalés, Aina ; Yavitt, F. Max ; Bera, Kaustav ; Andreu, Ion (ORCID: 0000-0002-8374-152X); Granero Moya, Ignasi ; Zalvidea, Dobryna (ORCID: 0000-0001-7770-037X); Kechagia, Zanetta ; Wiche, Gerhard ; Trepat, Xavier ; Ivaska, Johanna ; ANSETH, KRISTI ; Shenoy, Vivek ; Roca-Cusachs, Pere (ORCID: 0000-0001-6947-961X)
Publisher	CORA.Repositori de Dades de Recerca
Contributor	Roca-Cusachs, Pere; Institut de Bioenginyeria de Catalunya
Publication Year	2026
Funding Reference	https://ror.org/00k4n6c32 101097753 MechanoSynth ; https://ror.org/00k4n6c32 Adv-883739 Epifold ; https://ror.org/01bg62x04 2021 SGR 01425 ; https://ror.org/01bg62x04 Beatriu de Pinós 2020-BP 00211
Rights	CC0 1.0; info:eu-repo/semantics/openAccess; http://creativecommons.org/publicdomain/zero/1.0
OpenAccess	true
Contact	Roca-Cusachs, Pere (Institute for Bioengineering of Catalonia)

Representation
Resource Type	Experimental data; Dataset
Format	text/plain; text/csv
Size	34966; 22465; 15238; 14556; 24732; 7422; 52532; 30098; 2445; 21284; 11965; 7004; 23829; 4032; 42935; 12438; 9436; 8957
Version	1.1
Discipline	Basic Biological and Medical Research; Biology; Biophysics; Life Sciences; Medicine