Nano-scale free volume and encapsulation properties of biopolymers: opening it up at the molecular level.

DOI

Edible biopolymers are routinely used in the encapsulation and controlled release of bioactive ingredients (e.g. medicines, nutrients, flavours). Common encapsulants are in their glassy states. The encapsulation efficiency is governed by the molecular mobility (diffusion) through the biopolymer matrices, which is mediated by the naturally occurring disorder related nano-scale local free volume. Thus, an understanding of the relationship between molecular mobility and free volume is fundamental to a rational design of encapsulants rather than the current trial and error approach. This work proposes to combine neutron scattering to measure molecular mobility and recently developed Positron Annihilation Lifetime Spectroscopy (PALS) for direct measurement of ¿free volume¿ holes to progress towards the design of tailor made encapsulants for a specific bio-ingredient.

Identifier
DOI https://doi.org/10.5286/ISIS.E.24089666
Metadata Access https://icatisis.esc.rl.ac.uk/oaipmh/request?verb=GetRecord&metadataPrefix=oai_datacite&identifier=oai:icatisis.esc.rl.ac.uk:inv/24089666
Provenance
Creator Mr David Hughes; Professor Rob Richardson; Professor Ashraf Alam; Dr Rebecca Welbourn; Professor Stuart Clarke; Dr SEUNG YEON LEE; Dr Mina Roussenova
Publisher ISIS Neutron and Muon Source
Publication Year 2015
Rights CC-BY Attribution 4.0 International; https://creativecommons.org/licenses/by/4.0/
OpenAccess true
Contact isisdata(at)stfc.ac.uk
Representation
Resource Type Dataset
Discipline Photon- and Neutron Geosciences
Temporal Coverage Begin 2012-10-18T08:36:17Z
Temporal Coverage End 2012-10-24T08:12:56Z