AB-SR (AntiBody Sequence Reconstructor) software: datasets for complete benchmarking

DOI

Files, folders, tabular data and some raw data used in the publication: AB-SR reconstructs polyclonal antibody Fv domains after bottom-up proteomic de-novo sequencing (N. Maillet & B. Saunier).

The AB-SR software reconstructs the sequences of most pairs of heavy and light chain variable regions from (in silico) pools containing up to 500 immunoglobulins in just a few minutes. For each Figure, the data before and after AB-SR software are available (see README.md for detailed explanations).

Data presented here are used to benchmark AB-SR. More precisely, each experiment consists in IgGs coming from public databases being in silico digested using RPG software. Resulting peptides are then fed to AB-SR that reconstructs most initial IgGs.

AB-SR, 0.5.0

Identifier
DOI https://doi.org/10.57745/4RNESM
Metadata Access https://entrepot.recherche.data.gouv.fr/oai?verb=GetRecord&metadataPrefix=oai_datacite&identifier=doi:10.57745/4RNESM
Provenance
Creator MAILLET, Nicolas ORCID logo; SAUNIER, Bertrand ORCID logo
Publisher Recherche Data Gouv
Contributor Collection administrator; MAILLET, Nicolas; Institut Pasteur; Entrepôt-Catalogue Recherche Data Gouv
Publication Year 2023
Rights info:eu-repo/semantics/openAccess
OpenAccess true
Contact Collection administrator (Institut Pasteur); MAILLET, Nicolas (Institut Pasteur, Université Paris Cité, Bioinformatics and Biostatistics Hub, F-75015 Paris, France)
Representation
Resource Type Dataset
Format application/x-xz; text/markdown
Size 123771256; 826456268; 151168720; 167698664; 177197812; 13509
Version 1.0
Discipline Computer Science; Life Sciences; Biology; Medicine