The COVID-19 pandemic was making a huge impact on Europe’s healthcare systems in the spring of 2020, and most predictive models concurred that pandemic waves were in the offing. Most studies adopted a pathogenic approach to the subject; few used a salutogenic approach. These showed, however, that nurses can retain their health despite a pandemic by mobilising generalised resistance resources. Our study aims to understand how nurses working in hospitals protected their health and workplace well-being during the COVID-19 pandemic by investigating the moderating effects of the health resources they mobilised against the stressors inherent to the situation. Data was gathered longitudinally in the following countries: Switzerland (French-speaking and German-speaking parts), France, Portugal and Canada. In addition, a cross-sectionnal sample of nurses from Belgium was also investigated. The questionnaires included the PSS, WHOQOL, NSS, BRIEF-COPE, PTGI, CD-RISC, MSPSS, COPSOQ, SISI and demographic information. See Ortololeva et al. 2021 (in the bibliographical reference section) for the published protocol of this project