IntOGen - Cancer Drivers Database (2014)

DOI

This database contains information on the genes identified as drivers in Rubio-Perez and Tamborero et al. (2015). It contains information on driver identification at mutational, CNA and gene fusion level. Additional ancillary information about the role and major clonality of drivers is also included. A table is also provided with the list of datasets used for mutational driver identification.

File contents/n-----------------/nTumor_cohort_details.tsv/nDatasets of somatic mutations employed in the analysis to detect drivers/nCNA_drivers_per_tumor_type.tsv/nList of 29 CNA cancer driver genes in TCGA cohort./nFusion_drivers_per_tumor_type.tsv/nList of 10 fusion driver genes in TCGA cohort./nMutational_drivers_per_tumor_type.tsv/nList of 459 mutation driver genes in full cohort./nMutational_drivers_project_detection.tsv/nList of 459 mutation driver genes detected by project./nMutational_drivers_signals.tsv/nList of genes with at least 1 signal of positive selection across the 6792 samples./nMutational_drivers_count_frequency.tsv/n List of 459 mutational drivers the count of mutated samples across all tumor types./nDrivers_type_role.tsv/nList of 475 drivers, driver type (mutational, CNA and/or fusion driver) and its role in cancer/nDrivers_cloncal_frequency.tsv/nList of 666 genes for which we were able to compute clonal frequency

Identifier
DOI https://doi.org/10.34810/data429
Related Identifier IsCitedBy https://doi.org/10.1016/j.ccell.2015.02.007
Metadata Access https://dataverse.csuc.cat/oai?verb=GetRecord&metadataPrefix=oai_datacite&identifier=doi:10.34810/data429
Provenance
Creator Rubio Pérez, Carlota (ORCID: 0000-0002-1921-168X); Tamborero Noguera, David ORCID logo; Schroeder, Michael Philipp, 1986- ORCID logo; Antolín Hernández, Albert, 1984- ORCID logo; Déu Pons, Jordi ORCID logo; Pérez Llamas, Christian, 1976-; Mestres i López, Jordi ORCID logo; González-Pérez, Abel ORCID logo; López Bigas, Núria ORCID logo
Publisher CORA.Repositori de Dades de Recerca
Publication Year 2023
Rights Custom Dataset Terms; info:eu-repo/semantics/openAccess; https://dataverse.csuc.cat/api/datasets/:persistentId/versions/1.0/customlicense?persistentId=doi:10.34810/data429
OpenAccess true
Representation
Resource Type Clinical data; Dataset
Format text/tsv; text/plain
Size 1994; 49264; 17330; 933; 4109; 24540; 385478; 81340; 943; 4929
Version 1.0
Discipline Life Sciences; Medicine