Non-lamellar lipid-based liquid crystalline structures at interfaces - effect of surface properties on layer structure and composition

DOI

To understand better the properties of non-lamellar liquid crystalline nanoparticles, LCNP, as delivery vehicles or surface modifying systems, it is crucial to understand how they interact with different interfaces. The aim of this work is thus to reveal the interfacial properties of GDO-based LCNPs and to determine the effect of both particle and interfacial properties on the adsorption and the subsequently formed interfacial layer. We want to answer the following questions, by NR studies of the layer formation kinetics, using isotope labelled P80: 1. What role does the stabilizer play for the LCNP adsorption mechanism? Do the particles first adhere via the P80 and which component spread from the LCNP on the surface? 2. What is the location of the stabilizer P80 in terms of LCNP adhesion? How does the surface properties affect the composition of the layer adjacent to the surface?

Identifier
DOI https://doi.org/10.5286/ISIS.E.24090576
Metadata Access https://icatisis.esc.rl.ac.uk/oaipmh/request?verb=GetRecord&metadataPrefix=oai_datacite&identifier=oai:icatisis.esc.rl.ac.uk:inv/24090576
Provenance
Creator Dr Bob Thomas; Dr Fredrik Tiberg; Professor Tommy Nylander; Dr Maria Wadsäter; Dr Justas Barauskas
Publisher ISIS Neutron and Muon Source
Publication Year 2016
Rights CC-BY Attribution 4.0 International; https://creativecommons.org/licenses/by/4.0/
OpenAccess true
Contact isisdata(at)stfc.ac.uk
Representation
Resource Type Dataset
Discipline Photon- and Neutron Geosciences
Temporal Coverage Begin 2013-05-29T23:00:00Z
Temporal Coverage End 2013-06-03T07:49:46Z