We are a group of structural biologists based in Paris that would like to benefit from high-end data collection shifts at ESRF. Our research spans various life science fields: bacterial transporters (Biou, Broutin) and machineries (Bellinzoni, Gubellini, Mechaly, Petrella), nucleic acid research (Leulliot, Sauguet, Tisné), eukaryotic channels and receptors (Prevost, Venien-Bryan, Wolff), virus biology and vaccine development (Barba-Spaeth, Guardado Calvo). Our group is already active as a community and the local proximity allows us to meet regularly. We have good access to screening microscopes but would need data collection on 300kV systems to reach cutting-edge resolution.