This dataset contains data models, synthesis procedures, PXRD patterns, and analysis results underlying the article “Data-Model-Driven Management and Analysis of MOF Synthesis Data”. It includes a data model for MOF synthesis based on XDL and two example MOF synthesis datasets (Fe–terephthalate MOFs and MOCOF-1) with procedures and experimental product PXRD patterns, as well as phase mole fractions obtained by PXRD analysis and decision tree models. The folders are structured according to the type of data. The dataset is intended to support replication of the published analyses and reuse for method development in MOF synthesis data management.