SANS will be used to investigate the shear-induced alignment of the nematic phase of amyloid fibrils formed by designed octapeptides. The octapeptides will included sequenced and blocky peptides rich in arginine and phenylalanine such as RFRFRFRF and RRRRFFFF. In the former case, SAXS shows orientation under flow for a 1 wt% sample, however this was not controlled (it resulted from flow into a capillary delivery system at a synchrotron beamline) and there has been no prior systematic study of shear-induced orientation in such systems. SANS is well suited to this study because of the high contrast available using D2O as solvent as well as the elimination of beam damage (associated with longer X-ray experiments during kinetic shear-alignment measurements).