mPCRseq SNP typing for noninvasive samples from tigers and queen conch

For monitoring wildlife, genotyping DNA from noninvasively collected samples is a widely used method. However, the degraded and low quantity of DNA often recovered from such samples make it hard to obtain high quality genotypes, especially for microsatellites. We demonstrate the applicability of SNP-typing from noninvasive samples to monitor wildlife in two different species - tigers (Panthera tigris) and the Caribbean Queen conch (Strombus gigas).</p><p>We designed primers targeting about a hundred SNPs for both tigers and conch. The genotyping protocol involves a simple multiplex PCR where all targets are amplified in a single reaction. The products from each sample are barcoded and pooled before sequencing. Using this protocol we genotyped noninvasively collected tiger samples such as feces, hair and saliva. Using this data (~100 SNPs), we were able to identify unique individuals, discern relatedness between individuals, and detect population structure. We also genotyped conch fritters from restaurants along with some field-collected samples. We were able to detect population structure and identify related individuals.</p><p>Our study provides a proof-of-concept for a rapid, cost-effective, accurate and scalable method that can applied to conservation scenarios.

Identifier
Source https://data.blue-cloud.org/search-details?step=~01236B823FA6B2041E28866B0C45E84DBB2728C8B50
Metadata Access https://data.blue-cloud.org/api/collections/36B823FA6B2041E28866B0C45E84DBB2728C8B50
Provenance
Instrument Illumina MiSeq; Illumina HiSeq 2000; ILLUMINA
Publisher Blue-Cloud Data Discovery & Access service; ELIXIR-ENA
Publication Year 2025
OpenAccess true
Contact blue-cloud-support(at)maris.nl
Representation
Discipline Marine Science
Temporal Point 2019-03-16T00:00:00Z