Dataset from the findings of manuscript 'Mitigating Anaesthetic Emissions: CALF-20 for N₂O Capture from exhaled anaesthetic streams', where we highlight a Zn-based metal-organic framework, CALF-20, for high-efficiency nitrous oxide capture under clinically relevant conditions, showcasing opportunities for sustainable anaesthetic gas capture technologies.Dataset includes raw data and exported excel spreadsheets for: PXRD, FTIR, TGA, N2 adsorption isotherm, simulated computational gas adsorption isotherms and breakthrough analysis data. Formats included: .txt, .xlsx, .csv, .qps (can be opened by Quantachrome software), .spa (can be opened by Thermo Scientific OMNIC Series Software), .dat