We propose to extend structural investigations of microcrystals localized on TEM grids towards measurements at ambient conditions and low temperatures using the nano-focus setup of beamline ID11. Rare-earth metal pnictide chalcogenides REPnCh (RE = La-Nd; PnCh = BiSe, BiTe, SbS) will be investigated at temperatures down to 90 K to examine the formation of charge-density waves. Microcrystalline compounds of the Ta/Cu/S system obtained by the decomposition of the thermoelectric material TaCuS3 will be measured at low-temperature conditions to investigate the dynamical disorder of Cu atoms.