Differentiating structure-specific low-energy dynamics in tea-catechins

DOI

Tea-catechins differ in the molecular constitutions and stereochemistry, in-turn showing variance in their bioactivity and radical-scavenging potential. This evidences differing conformational preferences, suspected of manifesting themselves in deviations to low-energy vibrations and dynamics, with theoretical results showing these deviations to be particularly pronounced in the ~2-40 meV region. We propose tracking the low-energy vibrational dynamics of the 8 principal catechins found in green tea towards resolving this structure-activity relationship. The results will complement extensive Muon-spin determinations completed on HiFi , towards a fully-comprehensive and highly-impacting work falling in the areas of 'Healthy-aging' and 'Physics-of-life', with significant long-term potential to inform other anti-oxidant, nutritional sciences and health/life-sciences initiatives.

Identifier
DOI https://doi.org/10.5286/ISIS.E.47627857
Metadata Access https://icatisis.esc.rl.ac.uk/oaipmh/request?verb=GetRecord&metadataPrefix=oai_datacite&identifier=oai:icatisis.esc.rl.ac.uk:inv/47627857
Provenance
Creator Dr Svemir Rudic; Dr Gregory Chasse; Professor Neville Greaves; Dr Kun Tian; Miss Lily Hunnisett; Miss Huyen Trang Vu; Miss Hanieh Ghodrati; Miss zuharia arshad; Miss Si Man Lao; Ms Shi Min Tan
Publisher ISIS Neutron and Muon Source
Publication Year 2017
Rights CC-BY Attribution 4.0 International; https://creativecommons.org/licenses/by/4.0/
OpenAccess true
Contact isisdata(at)stfc.ac.uk
Representation
Resource Type Dataset
Discipline Biology; Biomaterials; Engineering Sciences; Life Sciences; Materials Science; Materials Science and Engineering
Temporal Coverage Begin 2014-03-12T00:00:00Z
Temporal Coverage End 2014-03-15T10:25:23Z