The proteome and secretome of rat liver sinusoidal endothelial cells in early primary culture, and effects of dexamethasone

DOI

LSECs from male Sprague Dawley rats were cultured on collagen type-I in 5% oxygen atmosphere in DMEM with serum-free supplements for 2-24h. Quantitative proteomics using a tandem mass tag (TMT)6-plex strategy on Q-Exactive mass spectrometer. The worksheet contains the normalized reporter intensities for the 3 biological replicates for 5 samples representing 2h control, 24h control, 24h+IL-1beta, 24h + Dex, 24h + Dex and IL-1 beta

Identifier
DOI https://doi.org/10.18710/AAJYOW
Related Identifier IsCitedBy https://doi.org/10.1371/journal.pone.0273843
Metadata Access https://dataverse.no/oai?verb=GetRecord&metadataPrefix=oai_datacite&identifier=doi:10.18710/AAJYOW
Provenance
Creator Bhandari, Sabin (ORCID: 0000-0003-3837-027X)
Publisher DataverseNO
Contributor Sørensen, Karen Kristine; UiT The Arctic University of Norway; Bruun, Jack-Ansgar; Bhandari, Sabin; Sørensen, Karen; Li, Ruomei; Martinez, Inigo; Urbarova, Ilona; Smedsrød, Bård; Simon-Santamaria, Jaione; Vascular Biology Research Group (VBRG)
Publication Year 2021
Funding Reference UiT The Arctic University of Norway
Rights CC0 1.0; info:eu-repo/semantics/openAccess; http://creativecommons.org/publicdomain/zero/1.0
OpenAccess true
Contact Sørensen, Karen Kristine (UiT The Arctic University of Norway)
Representation
Resource Type TMT-Sixplex labelled proteomic data; Dataset
Format text/plain
Size 15224; 1033243; 505727
Version 3.2
Discipline Life Sciences; Medicine
Spatial Coverage Proteomics and Metabolomics Core Facility (PRiME), UiT The Arctic University of Norway