This repository contains all observational data sets during CALISHTO campaign used for the paper: Gao, K., Vogel, F., Foskinis, R., Vratolis, S., Gini, M. I., Granakis, K., Zografou, O., Fetfatzis, P., Berne, A., Papagiannis, A., Möhler, O., Eleftheridadis, K., and Nenes, A.: On the drivers of ice nucleating particle diurnal variability in Eastern Mediterranean clouds, npj Climate and Atmospheric Science, Preprint link: https://www.researchsquare.com/article/rs-4378562/v1. CALISHTO campaign was conducted between 12 October and 27 November 2021 to observe ice nucleating particles and aerosol properties at the Helmos Hellenic Atmospheric Aerosol and Climate Change station in Eastern Mediterranean, to understand cloud-aerosol interactions. To evaluate the spatial-temporal variabilities and characteristics of ice nucleating particles, a high-time resolution ice nucleation spectrometer was employed and different online aerosol property measurements were conducted in-situ, including particle number concentration, particle size distribution, particle fluorescent properties, and particle chemical composition. In addition, planetary boundary layer conditions at the observation site were determined by remote sensing techniques employed at a lower site.