Establishment of organotypic epithelial raft cultures as a model of high-grade cervical intraepithelial neoplasia and quantification of treatment effects through machine learning-based cell counting [data]

DOI

This dataset contains the raw data and code used for analyses in the doctoral dissertation "Establishment of organotypic epithelial raft cultures as a model of high-grade cervical intraepithelial neoplasia and quantification of treatment effects through machine learning-based cell counting".

The data is comprised of annotations and cell detections in HE-stained sections from 3D organotypic raft cultures, as well as generated statistics and plots that are depicted in the results section of the corresponding doctoral dissertation. For instructions on how to navigate the dataset, run code and reproduce the results, please refer to the README file.

QuPath, 0.5.0

Python, 3.10.9

Python, 3.12.0

NDP.view, 2.9.29

Identifier
DOI https://doi.org/10.11588/data/AVIYB0
Metadata Access https://heidata.uni-heidelberg.de/oai?verb=GetRecord&metadataPrefix=oai_datacite&identifier=doi:10.11588/data/AVIYB0
Provenance
Creator Richard M. Köhler ORCID logo; Hans-Jürgen Stark; Iris Martin; Joel Altmann; Martin Simon Kalteis ORCID logo; Magnus von Knebel Doeberitz; Elena-Sophie Prigge
Publisher heiDATA
Contributor Richard M. Köhler; Magnus von Knebel Doeberitz
Publication Year 2024
Funding Reference Heinrich F.C. Behr foundation, German Cancer Research Center (DKFZ), Heidelberg, Germany MD thesis grant for Richard M. Köhler
Rights info:eu-repo/semantics/openAccess
OpenAccess true
Contact Richard M. Köhler (Movement Disorder and Neuromodulation Unit, Department of Neurology, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany)
Representation
Resource Type Tables of cell detections and cell counts derived from H&E stained sections; Dataset
Format application/zip; application/octet-stream; text/markdown
Size 39515; 11648; 131060598; 144; 304; 5296835; 2493
Version 1.0
Discipline Life Sciences; Medicine
Spatial Coverage Department of Applied Tumor Biology, University Hospital Heidelberg, Germany