Disease coverage, overlap and divergence of human genome-wide association studies and pharmaceutical research and development

DOI

Repository with the scripts used for the calculations in the manuscript "Disease coverage, overlap and divergence of human genome-wide association studies and pharmaceutical research and development". It could be used to revisit the estimates in the future.Overview of the scripts:- gwas_cat_mapping_code: includes the python code (.ipynb) used to map the traits in the GWAS Catalog to UMLS terms as described in Materials and Methods.- gwas_clinicaldev_code: includes the python code (.ipynb) used to identify the human diseases evaluated in drug development and in GWAS as s described in Materials and Methods. It also includes the code to generate Figure 1, Figure 2 and Figure 4 of the manuscript.

Identifier
DOI https://doi.org/10.5522/04/25541392.v1
Related Identifier https://ndownloader.figshare.com/files/45535575
Related Identifier https://ndownloader.figshare.com/files/45535581
Metadata Access https://api.figshare.com/v2/oai?verb=GetRecord&metadataPrefix=oai_datacite&identifier=oai:figshare.com:article/25541392
Provenance
Creator Gordillo-Maranon, Maria
Publisher University College London UCL
Contributor Figshare
Publication Year 2024
Rights https://creativecommons.org/licenses/by-nc-sa/4.0/
OpenAccess true
Contact researchdatarepository(at)ucl.ac.uk
Representation
Language English
Resource Type Dataset
Discipline Other