Polymer Chain exchange mechanism of complex coacervate core micelles (C3Ms) - Anionic homopolymer

DOI

Complex coacervates have been studied for a long time for their medical applications and unusualphysical-chemical properties: they are dense networks of poly-electrolytes, that dissolve instead offlocculating when exposed to high salt concentrations. Despite being dense, they are fullypermeable to water, yet they are capable of strongly binding heavy metal ions or large (bio-)molecules, making them useful as drug carriers. By modifying them to form micelles, the micellecores become small coacervate networks; Complex Coacervate Core Micelles (C3Ms). Unlikegels, they are dispersed into solution easily and have an enormous active surface area. The formand structure of C3Ms are quite well known, but the exchange mechanism of polymers betweenmicelles is unknown. By performing contrast decay time-resolved SANS, we will determine ifpolymers migrate separately or not.

Identifier
DOI https://doi.org/10.5286/ISIS.E.84803801
Metadata Access https://icatisis.esc.rl.ac.uk/oaipmh/request?verb=GetRecord&metadataPrefix=oai_datacite&identifier=oai:icatisis.esc.rl.ac.uk:inv/84803801
Provenance
Creator Dr Ilja Voets; Dr Robert Dalgliesh; Dr Ad van Well; Professor Katia Pappas; Mr Jurrian Bakker; Dr Wim Bouwman
Publisher ISIS Neutron and Muon Source
Publication Year 2020
Rights CC-BY Attribution 4.0 International; https://creativecommons.org/licenses/by/4.0/
OpenAccess true
Contact isisdata(at)stfc.ac.uk
Representation
Resource Type Dataset
Discipline Chemistry; Natural Sciences
Temporal Coverage Begin 2017-03-02T00:00:00Z
Temporal Coverage End 2017-03-07T00:00:00Z