Micro-Metagenomics: CharacterisingVirus-Surface Interactions Under Static & Shear Flow for Novel Microfluidic Design

DOI

Traditional methods of viral detection are based on the isolation and culture of viral pathogens, but often viruses cannot be cultivated under laboratory conditions, constituting a substantial barrier to viral diagnostics and discovery. Microfluidics is a multidisciplinary field in which low volumes of fluids are used in high-throughput screening. Therefore, when combined with appropriate system and filter designs, microfluidics could make the ideal technology for the filtering, detection and quantification of viruses within a sample. This proposal is an integral part of a one year pump- prime project to analyse the properties of viruses which differ substantially in size, shape & deformability on different microfluidic surfaces. This information from neutron reflectivity and scattering will be used to inform mathematical modelling leading to initial trial microfluidic devices.

Identifier
DOI https://doi.org/10.5291/ILL-DATA.9-12-513
Metadata Access https://data.ill.fr/openaire/oai?verb=GetRecord&metadataPrefix=oai_datacite&identifier=10.5291/ILL-DATA.9-12-513
Provenance
Creator Tushingham, George; Yoldi, Irantzu; Gutfreund, Philipp; Orton, Richard; Barker, Robert; Krueger, Timm
Publisher Institut Laue-Langevin
Publication Year 2018
Rights OpenAccess; info:eu-repo/semantics/openAccess
OpenAccess true
Representation
Resource Type Dataset
Size 2 GB
Version 1
Discipline Particles, Nuclei and Fields