The specific binding of cholera toxin subunit B to the ganglioside GM1 is a system with importance both as a model biophysical system, as a marker for lipid rafts in biology when used as a fluorescent conjugate and as a functional component in some targeted drug delivery systems. All of these uses exploit the fact that this is the highest affinity binding known between a protein and a lipid. We wish to study how protein binding affects membrane properties so in our case this seems a sensible target system.We have already performed neutron measurements both by SANS and NSE which confirm that this is indeed feasible and demonstrate interesting results. These previous experiments have identified further measurements which would build on the quality of the results already obtained and assist in assuring confidence in our analysis.