This dataset contains records of planktic foraminiferal δ¹⁸O, bulk sedimentary δ¹⁵N, alkenone concentrations and opal content of sediment core MD01-2380, which was retrieved in the central Banda Sea (5°45.64' S, 126°54.25' E, 3232 m water depth). These records cover the last ⁓800 kyrs.Stable oxygen isotope analysis on planktic foraminifera Globigerinoides ruber tests (size fraction 250-355 µm) were performed at MARUM, University of Bremen using a Finnigan MAT 251 mass spectrometer with Kiel I devices. The internal carbonate standard is a Solnhofen Limestone, which is calibrated to the National Bureau of Standards (NBS) 19 standard. The long-term analytical precision is better than ±0.07‰.Sedimentary δ¹⁵N was analyzed at the Yale Analytical and Stable Isotopic Center YASIC (Yale University), using a Costech ECS 4010 Elemental Analyzer with Conflo III interface. The precision of the isotopic analyses based on in-house standard measurements of ±0.2 ‰.Biogenic opal of MD01-2380 was determined at Dalhousie University following methods developed by Mortlock and Froelich (1989; doi:10.1016/0198-0149(89)90092-7).Alkenone concentrations were measured at the National Taiwan Ocean University, following the method of Yamamoto et al. (2000).