Data publication: Development and Evaluation of Deuterated [18F]JHU94620 Isotopologues for the Non-invasive Assessment of the Cannabinoid type 2 Receptor in Brain

DOI

What is already known • Increased expression of the CB2R in the brain is linked to certain neuropathological diseases. • First clinical trials for CB2R-directed therapies are conducted. What this study adds • [18F]JHU94620-d8 provides the potential to quantify the CB2R receptor density in the brain by positron-emission-tomography. Clinical significance • Stratification of patients for CB2R-directed therapies and follow up of the treatment response is needed.

Identifier
DOI https://doi.org/10.14278/rodare.3149
Related Identifier IsIdenticalTo https://www.hzdr.de/publications/Publ-39600
Related Identifier IsReferencedBy https://www.hzdr.de/publications/Publ-39547
Related Identifier IsPartOf https://doi.org/10.14278/rodare.3148
Related Identifier IsPartOf https://rodare.hzdr.de/communities/rodare
Metadata Access https://rodare.hzdr.de/oai2d?verb=GetRecord&metadataPrefix=oai_datacite&identifier=oai:rodare.hzdr.de:3149
Provenance
Creator Gündel, Daniel ORCID logo; Teodoro, Rodrigo; c, Friedrich-Alexander Ludwig a.; Heerklotz a., Anne; Toussaint, Magali ORCID logo; Deuther-Conrad, Winnie ORCID logo; Bormans d., Guy; Brust a., Peter; Kopka, Klaus ORCID logo; Moldovan, Rares-Petru ORCID logo; f, Rareş-Petru Moldovan
Publisher Rodare
Publication Year 2024
Rights Creative Commons Attribution 4.0 International; Open Access; https://creativecommons.org/licenses/by/4.0/legalcode; info:eu-repo/semantics/openAccess
OpenAccess true
Contact https://rodare.hzdr.de/support
Representation
Resource Type Dataset
Discipline Life Sciences; Natural Sciences; Engineering Sciences