Genome-wide meta-analysis of iron status biomarkers and the effect of iron on all-cause mortality in HUNT

DOI

This dataset contains the GWAS meta-analysis summary statistics for serum ferritin from the preprint “Genome-wide meta-analysis of iron status biomarkers and the effect of iron on all-cause mortality in HUNT”.

Iron is essential for many biological processes, but iron levels must be tightly regulated to avoid harmful effects of both iron deficiency and overload. Here, we perform genome-wide association studies on four iron related biomarkers (serum iron, serum ferritin, transferrin saturation, total iron binding capacity) in the Trøndelag Health Study (HUNT), the Michigan Genomics Initiative (MGI) and the SardiNIA study, followed by their meta-analysis with publicly available summary statistics, analyzing up to 257,953 individuals.

Identifier
DOI https://doi.org/10.18710/S9TJEL
Related Identifier https://doi.org/10.1038/s42003-022-03529-z
Metadata Access https://dataverse.no/oai?verb=GetRecord&metadataPrefix=oai_datacite&identifier=doi:10.18710/S9TJEL
Provenance
Creator Moksnes, Marta Riise (NTNU - Norwegian University of Science and Technology); Hveem, Kristian (NTNU - Norwegian University of Science and Technology); Willer, Cristen (University of Michigan); Brumpton, Ben (NTNU - Norwegian University of Science and Technology)
Publisher DataverseNO
Contributor Moksnes, Marta Riise; Norwegian University of Science and Technology; NTNU Open Research Data
Publication Year 2022
Rights CC0 Waiver; info:eu-repo/semantics/openAccess; https://creativecommons.org/publicdomain/zero/1.0/
OpenAccess true
Contact Moksnes, Marta Riise (NTNU - Norwegian University of Science and Technology)
Representation
Resource Type Summary statistics (results) from GWAS analysis.; Dataset
Format text/plain
Size 8467; 1076888666; 1297386528; 1297827626; 1131753745
Version 2.0
Discipline Life Sciences; Medicine