The recruitment of fluorinated therapeutic agents and biomarkers at interfaces is an important new focus in drug delivery research with implications in the treatment of cancers and neurodegenerative diseases. We have shown recently that the adsorption in phospholipid monolayers of soluble fluorinated compounds can be strongly enhanced by hydrophobic interactions at the air/water interface with fluorocarbon gases. In December 2016, we achieved neutron reflectivity experiments on FIGARO that successfully allowed quantification of the composition of the interfacial film and interaction kinetics for the first time (#9-13-662). We have unequivocally confirmed and quantified the irreversible recruitment of biomarkers in condensed-phase lipid monolayers. Now we propose to investigate the behaviour of 1) a short fluorocarbon gas (C4F9) in order to quantify the extent of the attractive interactions, and molecular recognition, arising between the fluorocarbon and the fluorinated moiety of the biomarkers, and 2) the diffusion kinetics of the deuterated fluorinated biomarkers, which turned out from our first experiments, to be significantly different from those of the hydrogenous ones.