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Determination of the absorbed amount and location of a hydrophobic drug in su...
Many drugs are both poorly water-soluble (hydrophobic) and lipophilic in nature and are therefore incorporated into surfactant micelles and monolayers. As the incorporation of... -
Kinetic Study of the Mechanistic Complexation Process Between DNA and Cationi...
We propose to use the new SANS2d to study the dynamic structural evolution in the couse of the formation of DNA-cationic polymer complexes. The dynamic process and the mixing... -
Steroidal drug containing dodecyl sulphate monolayers: effect of counterion
An number of potential drugs, including steroidal drugs are extremely water insoluble, limiting their commercialisation as medicines. Solubilisation of drug in surfactant... -
Adsorption of liquid crystal nanostructured particles to model hydrophilic an...
Cubosomes and hexosomes are particles with internal liquid crystal structures of the bicontinuous cubic or reverse hexagonal nanostructures respectively. The nanostructure... -
Lipopolysaccharide Functions as Bacterial Receptors to Antimicrobial Peptides
Neutron reflection (NR) is well established for studying molecular films such as lipid monolayers. Its high depth resolution combined with deuterium labelling can determine the... -
Effect of structure on the location of hydrophobic drugs in ionic surfactant ...
Many drugs are both poorly water-soluble (hydrophobic) and lipophilic in nature and are therefore incorporated into surfactant micelles and monolayers. As the incorporation of...
