9 datasets found

In recent years nano- and microparticles composed of polymeric or lipid material have been proposed as drug carriers. Their use allows the modification of the biopharmaceutic...

Nanodiscs are self assembled complexes of phospholipids and a class of amphipathic helical proteins termed membrane scaffold proteins . The proteins and lipids self-assemble...

A family of sterol-modified glycerophospholipids (SML) have been synthesized in which the sn-1 or sn-2 position is covalently attached to cholesterol and the alternative...

A family of sterol-modified glycerophospholipids (SML) have been synthesized in which the sn-1 or sn-2 position is covalently attached to cholesterol and the alternative...

We have previously solved the structure by SANS of the complex between the outer membrane protein F of E coi and the toxin colicin N which is a large antibiotic protein. This...

Mucus is a bio-gel, an opaque and slimy secretion that forms a continuous ¿blanket¿ adherent to epithelial surfaces in mammalian organs (eye, nose, conductive airways,...

Our objective is to create asymmetric solid surface tethered bilayers (tBLMs) with the the outer leaflet predominately populated by charged phospholipids. tBLMs are produced by...

This experiment is part of a programme to study the effect of applied electric fields on the structure of biomimetic films formed at Au electrodes, with emphasis on...

Progress in the development of nano-sized hybrid therapeutics and nano-sized drug delivery systems - "nanomedicines" - over the last decade has been remarkable. One key...