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Further SANS contrast measurements on important protein/DNA interactions from...
This proposal is to perform further SANS contrast measurements on three protein/DNA interactions currently worked on at the Research Complex at Harwell. This is part of an... -
In situ study of stainless steel martensitic transformation at cryogenic temp...
The mechanical properties of of austenitic stainless steels are thought to be improved by the phenomenon of deformation-induced martensitic transformation, which acts to... -
Magnetic structures of antiferromagnetic heavy fermion CeAuAl3 and CeCuAl3 co...
CeAuAl3 and CeCuAl3 compounds crystallize in the tetragonal I4mm, BaNiSn3-type and display interesting bulk properties. Here we propose to investigate the magnetic structures of... -
Solution structures of the immunologically important proteins IgA, C3 and IgG
Abnormally glycosylated IgA leads to IgA nephropathy, the most common cause of renal failure. IgG antibody represents one-third of new drugs currently in development, and its... -
SANS contrast measurements on important protein/DNA interactions from RCaH
This proposal is to perform SANS contrast measurements on three protein/DNA interactions currently worked on at the Research Complex at Harwell. This is part of an ongoing... -
Neutron reflection from 3He layer adsorbed on liquid 4He surface
More than four decades ago A. F. Andreev predicted theoretically the existence of quantum states of 3He atoms on free surface of liquid 4He . In other words, at low... -
Self-Organisation of Phospholipids on Au Electrodes
This experiment is part of a programme to study the effect of applied electric fields on the structure of biomimetic films formed at Au electrodes, with emphasis on... -
Network compression and pressure-induced amorphisation in Zn(CN)2
Zn(CN)2 is an important material because it shows isotropic NTE over a large temperature range and to an extent more than double that of ZrW2O8. This unusual behaviour... -
Quasielastic scattering in stuffed spin ices: defects or low lying singlets?
The subjects of this proposal, Ho2+xTi2-xO7-x/2, are brand new materials1 related to Ho2Ti2O7, a spin ice2,3. They have the remarkable property of remaining disordered at very... -
Isotope dependence of the Néel Temperature in cuprates
The effect of isotope exchange on the Néel temperature in the cuprates was neer determined because it was impossible to perform relaible isotope exchanges in the parent... -
Solution structures of the immunologically important proteins IgG and C3b
IgG antibody represents one-third of new drugs currently in development. We will unravel the solution structures of the Fab and Fc fragments within IgG. Following our earlier... -
Investigation of phase diagrams of polysaccharides
This project concerns fundamental and strategically important research underlying the development of new drug delivery vehicles. We propose to sample phase diagram of... -
Spin Coherent Transport in Organic Spin-Valves
We have recently performed a `proof-of-principle' Low Energy Muon Spin Rotation experiment on an organic spin valve. In an extension to our muon measurements and an attempt to... -
A model system to study the important interactions of proteins from extreme e...
Organisms which live in the presence of large quantities of salt are known as halophilic (meaningsalt-loving). Halophilic proteins are of great interest due to their ability to... -
Is cloud water nitrate radical chemistry important in oxidising thin films on...
Projected climate change is strongly influenced by clouds. The oxidative processing of pollutants in clouds affects droplet size and reflectivity, important climatic effects.... -
Enhanced oxygen hyperstoichiometry in Y doped La9.33+xGe6O26+3x/2
Apatite-type lanthanide silicates/germanates have been attracting considerable interest as a new class of oxide ion conductors. The presence of interstitial oxide ions is... -
Mesostructured titania films from ethanolic solutions
In this proposal we wish to continue our current work on mesostructured inorganic films in largely ethanolic solutions, containing limited amounts of water. Transition metal... -
Mechanical twinning in quartz rocks: in situ experiments at stress and during...
Previous experiments at ENGIN-X (Wenk et al. 2007) established that quartz rocks undergo mechanical twinning if stressed above 100 MPa. The amount of twinning is highly... -
Solution structures of the immunologically important proteins IgA and C3b
We are unravelling the solution structures of the Fab and Fc fragments in the IgA antibody family important in mucosal immunology. Having completed the structures for IgA... -
SANS Investigation on Packing Structure of Proteasome Activator 28
Proteasome plays an important role in the processing of antigenenic proteins for presentation by the MHC class I pathway. PA28 is an activator of the 20S proteasome, a large...
