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Studying the lateral organisation of mixed phospholipid bilayers by diffuse n...
Off-specular neutron reflection is potentially a powerful technique for studying the lateral organisation of phospholipid bilayers. However, this has not yet been demonstrated.... -
Measuring phospholipid flip-flop rates across vesicle bilayers
Asymmetry across biological membranes is vital for a wide range of organelle and cellular functions. Significant differences in lipid composition have been found between the... -
Floating Bilayers Deposited on Au / Fe Surfaces
There is currly great interest in the use of neutron reflection to study model bilayers. We have produced a model membrane system that is strongly associated with the substrate,... -
Insoluble layer formation in polymer bilayers
In a previous neutron reflectivity(NR) measurement (RB620370) on CRISP, we showed that the insoluble interlayer formed between the charge injection layer and a semiconducting... -
Phospholipid exchange between tethered bilayers and vesicles
Our objective is to create asymmetric solid surface tethered bilayers (tBLMs) with the the outer leaflet predominately populated by charged phospholipids. tBLMs are produced by... -
Calcium mediated interaction between siRNA and phospholipid bilayers: the eff...
The main objective of the present study is to gain an understanding of the nature of the interaction of ¿phospholipid membranes¿ with small, interfering RNA (siRNA) in the... -
Investigating the response of lipid bilayers to physically structured substrates
The functionality of biological membranes is closely tied to their structural behavior. To understand this behavior we propose to study the conformality of artificial lipid... -
Binding of DNA to Model Membranes in the Presence of Ca2+ Ions and a Membrane...
The aim of the present work is to gain an understanding of the interaction of DNA with the phospholipid bilayers. The effect of different forms of DNA, the presence of divalent... -
The interaction of cytochrome c with floating bilayers containing negatively ...
As research on apoptosis has gained momentum, the importance of membrane lipids in this crucial cellular process is becoming clear.Previously, we have determined using NR and...