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The effect of polymer therapeutics on the structure of mucin solutions toward...
Progress in the development of nano-sized hybrid therapeutics and nano-sized drug delivery systems - "nanomedicines" - over the last decade has been remarkable. One key... -
Polymer chain conformations in solutions for electrospinning
This proposal is part of a research programme which is focused on nano-fibres prepared by electrospinning. The programme is centered on developing an understanding of the... -
Investigation on the structural properties of doxorubicin-loaded PEGylated li...
Doxil® is a marketed liposomal formulation containing the anticancer drug doxorubicin. Recently, SAXS measurements have evidenced a crystalline fibrillar structure for the... -
Probing bulk heterojunction (BHJ) thin films with graded morphologies using SANS
This projects aims to contribute to a better understanding of the relationship between processing conditions, active layer morphology and device performance in polymer solar... -
Aggregation behaviour of PEGylated ibuprofen
In the present study the acidic, anti-inflammatory drug, ibuprofen has been PEGylated using an polyoxyethylene chain of 750 molecular weight. The consequence of this PEGylation... -
Cubosomes as biosensors: A kinetic study of changes to lattice parameter and ...
Lipid bicontinuous cubic phases are self-assembled three dimensional lattices, consisting of a single periodic bilayer interwoven by two independent water channels. They can be... -
Morphology and Phase Diagram of Thermoresponsive Polymer-Protein Conjugates
Using an enzyme mediated conjugation method we have prepared well-designed protein-polymer conjugates using a model protein, green fluorescent protein (GFP) with... -
Reconstitution of human dihydroorotate dehydrogenase into lipid-detergent mic...
Human dihydroorotate dehydrogenase (DHODH) is an integral membrane protein found in mitochondria involved in the biosynthesis of pyrimidines. DHODH oxidizes dihydroorotate with... -
SANS study of the effect of thermal annealing on the morphology of bulk heter...
This projects aims to contribute to a better understanding of the relationship between processing conditions, active layer morphology and device performance in polymer solar... -
Nanoscale zerovalent iron (nZVI) impact on soil microbial communities
The use of nanoparticles for environmental remediation is an emerging technology. Pioneering the field is the use of nanoscale zerovalent iron (nZVI) to cleanup ground waters... -
Non-equilibrium kinetics in highly interacting polymer mixtures
We seek to investigate the non-equilibrium phenomena of a model polymer mixture by time-solved SANS and temperature jump experiments within (a) one-phase region and (b) one to... -
HC-polymer 3D-network conjugated by hydrocarbon-fluorocarbon core/shell aggre...
For the last two decades, many polymers have been tested to increase CO2 viscosity for enhanced oil recovery. Unfortunately, HC-polymers were found to be inactive for the... -
Designing nanoscale polymeric structures: examining the breakdown of the Cahn...
Demixing of polymer blends via spinodal decomposition provides an effective means to generate polymer bicontinuous nanostructures with applications in membranes for separations... -
The influence of chemical pressure on the helimagnetic correlatations and sky...
The recent discovery of skyrmions and skyrmion lattices in materials with no inversion symmetry and their corresponding potential applications of Skyrmions in magnetic... -
Detailed structures of surfactant micelles
Measurements are required for Sans2d resolution checks and also the overlap of the two Sans2d detectors. Proposal submitted to panel and they deemed it should be done as... -
Effect of End Group on RAFT-Polymers for Lipid Nanodisc Stabilisation
Polymer stabilized lipid nanodiscs offer enormous potential as tools for enabling membrane protein structural studies & biophysics. Previously we studied discs formed using... -
Encapsulation of hydrophobic species in mixed micelles in polymer solutions
This proposal continues our investigations into film-forming polyelectrolyte-surfactant solutions. We have found that mixed micelle systems offer greater control over micelle... -
Centrifugal Force Spun Fibres
Centrifugal force spinning is a technique that has recently come into light as an easy route to producing large quantities of nano- to micro- scale polymer fibres in a short... -
Hydration effects in gels for water splitting.
Storing the energy available from the sun as a fuel that can be used anytime is a major global challenge. Organic materials synthesised from abundant elements that can harness... -
Interaction of a pH-sensitive Polymer with a Model Lipid Membrane in the Form...
This SANS experiment was proposed by 4 PhD students from 3 different institutions in a Marie-Curie Training Network. They are all in the second year of their PhD and their...