46 datasets found

This is a large scale project with the sequencing co-funded by collaborators at the University of Cape Town and WT Core (I2818). This is a project aimed at deepening our...

Data published as part of the Jouet et al. paper where the assay Deeplex Myc-TB is evaluated on mycobacterial identification and anti-tuberculous drug resistance prediction.

M. marinum isolate comparison during outbreak investigation

Mycobacteriosis caused by Mycobacterium marinum is a chronic bacterial infection that may cause a disease in both humans and fish. In this study we isolated and molecularly...

To investigate the transcriptome of Mycobacterium marinum at log phase and early stationary phase

Mycobacterium Marinum Mycobacterium Bovis.

Due to the rise of drug resistant forms of tuberculosis there is an urgent need for novel antibiotics to effectively combat these cases and to shorten treatment regimens....

PacBio sequencing of the Mycobacterium marinum type strain DSM 44344 (ATCC 927)

We performed a CRISPRi analysis to look for genes that were enriched or depleted during the treatment of several antibiotics including macozinone, ethionamide, bedaquiline and...

We performed a whole genome sequencing of resistant strains of Mycobacterium marinum against a hit compound from a high-throughput screening for novel anti-tuberculosis compound

Mycobacterium marinum is a free-living bacterium, which causes opportunistic infections in humans. This strain 927 was firstly isolated from soft water fish in 1926 by Aronson...

Tuberculosis remains the most pervasive infectious disease and the recent emergence of multiple or even fully drug-resistant strains increases the risk and emphasizes the need...

Nanopore Sequencing of Mycobacterium Marinum Infection

Regulation of M. marinum gene expression in an espM deletion strain Overall design: M Marinum M based strains (Wild type, epsM mutant and complemented overexpressor strain) were...

The mechanisms of action of compound 8 in Mycobacterium marinum although it inhibits the secretion of the bacteria. In this experiment, we aim to investigated the effect of...

Here, we identified a long-chain acyl-CoA-responsive transcriptional repressor, FdmR, as the key regulator of mycobacterial fatty acid catabolism. We employed RNA-Seq to...

To prove transmission of Mycobacterium marinum in an aquarium tank, we conducted phylogenetic analyses based on whole genome sequencing data of M. marinum strains from animal...

Here, we report the discovery of a novel mechanism of genetic complementation in M. marinum. We found that nonsense suppression was causing genetic complementation. Nonsense...

RNA-Seq of modern Beijing and ancient Beijing strains